Tamoxifen Citrate - A Potential Therapy for the Treatment of Keloids
Author(s): Glasnapp Andrew
Issue: Sep/Oct 1999 - Natural Hormone Replacement Therapy
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Page(s): 380-381
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Abstract: Keloid scar formation is a significant problem affecting millions of patients annually. Proposed management or prevention of keloids includes three distinctly different therapeutic approaches: correction of abnormal collagen metabolism when the equilibrium between collagen synthesis and degradation has been destroyed, alteration of the immune/inflammatory response and manipulation of the mechanical properties of wound repair. There currently is no universally accepted treatment modality resulting in permanent keloid scar ablation. The author discusses the pathology of keloids and tamoxifen citrate (efficacy and description). He also provides a Formula for Tamoxifen Citrate Cream 0.1% (100 g).
Related Keywords: collagen, fibrosis, hypertrophic scar, keloids, tamoxifen citrate, wound repair