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The Current Landscape of Veterinary Compounding in the Veterinary Setting

Author(s):  Gochenauer Alexandria E, Rishniw Mark, Holmes Erin R, Forsythe Lauren R

Issue:  Sep/Oct 2019 - Volume 23, Number 5
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Abstract:  Compounding for veterinarians is regulated by the U.S. Food and Drug Administration, but day-to-day regulation is deferred to the state authorities. Veterinarians must meet certain standards when prescribing or dispensing a compounded medication. Veterinarians are expected to maintain current knowledge of the benefit of compounded preparations and prescribe and dispense in keeping with the best evidence related to animal and human health. Whether veterinarians recognize or adhere to these standards is unknown. A self-administered survey was distributed electronically to 30,000 email addresses on record with the Veterinary International Network. The survey asked questions about the regulations and standards associated with the use of or prescription of compounded medications. Of the distributed surveys, 1,520 survey responses were received, for a 5.1% response rate. All surveys were included in the final analysis. Respondents with a higher training level in compounding had a greater perceived skill level regarding compounding of medications (r = 0.26, P<0.0001). Similarly, respondents with a higher training level had a greater knowledge of state laws and regulations (r = 0.14, P<0.0001). Those with formal training had better scores on the assessment questions than those with informal or no training (P=0.01). Approximately one-third of the respondents felt that they were not knowledgeable at all about compounding rules and regulations. The most common compounded medications used in practice by veterinarians are methimazole, metronidazole, and doxycycline. Veterinarians mostly recognized that compounding backordered, commercially available products is permitted. Formal training improves familiarity with compounding rules, regulations, and current practices. Therefore, efforts should be directed at improving veterinary knowledge of laws and regulations surrounding the practice of compounding medications.

Related Keywords: Alexandria E. Gochenauer, PharmD, FSHVP, Mark Rishniw, BVSc, MS, PhD, DACVIM (Cardiology, Internal Medicine), Erin R. Holmes, PharmD, MS, PhD, FAPhA, FACVP, Lauren R. Forsythe, PharmD, DICVP, FSHVP, veterinarian survey, veterinary pharmacy regulations, veterinary compounding training, veterinary medications, veterinarian education


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