Accuracy in Prescriptions Compounded by Pharmacy Students
Author(s): Shrewsbury Robert P, Deloatch Kimberly H
Issue: Mar/Apr 1998 - Pain Management
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Page(s): 139-142
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Abstract: Most compounded prescriptions are not analyzed to determine
the accuracy of the employed instruments and procedures. The assumption
is that the compounded prescription will be ± 5% the
labeled claim. Two classes of School of Pharmacy students who received
repeated instruction and supervision on proper compounding
techniques and procedures were assessed to determine
their accuracy of compounding a diphenhydramine hydrochloride
prescription. After two attempts, only 62% to 68% of the students
could compound the prescription within ± 5% the labeled claim;
but 84% to 96% could attain an accuracy of ± 10%. The results
suggest that an accuracy of ± 10% labeled claim is the least variation
a pharmacist can expect when extemporaneously compounding
prescriptions.
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