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Low-Dose Naltrexone: A New Therapy Option for Complex Regional Pain Syndrome Type I Patients

Author(s):  Sturn Kayla M, Collin Michael

Issue:  May/Jun 2016 - Volume 20, Number 3
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Abstract:  Naltrexone (an opioid antagonist) has long been used in patients overcoming alcohol and opioid dependency. However, at doses one-tenth of those commonly prescribed for the above conditions, an unexpected effect occurs that aids in alleviating pain. Although there are currently no randomized clinical trials supporting the use of low-dose naltrexone, we present a case study describing the impact of compounding low-dose naltrexone that has dramatically improved the patient’s pain symptoms which were refractory to other treatments.

Related Keywords: Kayla M. Sturm, PharmD Candidate, Michael Collin, RPh, FIACP, low-dose naltrexone, opioid antagonist, complex regional pain syndrome type I, extremity pain, CRPS, chronic pain syndromes, neuropathic pain, patient distress, case study, adverse effects, drug interactions, formulation

Related Categories: FORMULATIONS, PAIN MANAGEMENT, CASE REPORTS, ADVERSE DRUG EVENTS, NEUROLOGY

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