Basics of Sterile Compounding: Sterilization Methods in Sterile Product Manufacturing

Author(s):  Akers Michael J

Issue:  May/Jun 2024 - Volume 28, Number 3
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Abstract:  Sterilization methods to produce sterile preparations include heat, gas, radiation, and filtration. This article focuses on heat, gas, and radiation sterilization, plus a brief introduction to bright-light sterilization. Microbiology basics and microbial death kinetics, key to understanding why these sterilization methods work, will also be briefly discussed. Filtration sterilization will be covered in a separate article.

Related Categories: ENVIRONMENTAL , STERILE PREPARATIONS, UNITED STATES PHARMACOPEIA CONVENTIONS

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