Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

The Basics of Compounding: Compounding Gels

Author(s):  Allen Loyd V Jr

Issue:  Sep/Oct 1999 - Natural Hormone Replacement Therapy
View All Articles in Issue

Abstract:  Gels have a variety of applications in the administration of medications. In this article, the author covers definitions, classification of gels, gel-forming agents, preparation, common ingredients (alginic acid, bentonite, carbomer resins, carboxymethylcellulose, carboxymethylcellulose sodium/sodium carboxymethylcellulose, colloidal silicon dioxide, gelatin, magnesium aluminum silicate, methylcellulose, Plastibase/Jelene, poloxamer, polyvinyl alcohol, povidone, propylene glycol alginate, sodium alginate, tragacanth gum and Liqua-Gel), quality control, storage and stability. Tables provide a listing of general classifications and descriptions of gels and typical properties of selected carbopol pharmaceutical resins. The following example formulations are also provided: Poloxamer Gel Base, Lubricating Jelly Formula, Clear Carbomer Gel, Pluronic Lecithin Organogel (PLO Gel), Methylcellulose Gels and Piroxicam 0.5% in an Alcoholic Gel.

Related Keywords: acacia, bentonite magma, carbopol, gels, hydrogels, jellies, Liqua-Gel, magma, mucilages, organogels, piroxicam, Plastibase, pluronic F-127, pluronic lecithin organogel, poloxamer gel base, polyvinyl alcohol, povidone, propylene glycol alginate, sodium alginate, syneresis, thixotropy, tragacanth gum, viscosity


Printer-Friendly Version

Download in electronic PDF format for $55

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
The Basics of Compounding: Compounding Gels Allen Loyd V Jr Sep/Oct 1999 385-389 Buy
BHR in PLO Gel (Benadryl, Haldol, and Reglan in Pluronic Lecithin Organogel) Allen Loyd V Jr Jul/Aug 2021 322 Buy
The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP Allen Loyd V Jr May/Jun 2003 180-183 Buy
Ketoprofen 10%, Ibuprofen 10%, Cyclobenzaprine Hydrochloride 2%, and Piroxicam 2% in Pluronic Lecithin Organogel Gel Allen Loyd V Jr May/Jun 2011 245 Buy
Effect of Formulation pH on Transdermal Penetration of Antiemetics Formulated in Poloxamer Lecithin Organogel Woodall Rachel, Arnold John J, McKay Doug, Abill C Scott May/Jun 2013 247-253 Buy
Basics of Compounding for Cold Sores or Fever Blisters Allen Loyd V Jr May/Jun 2004 206-209 Buy
Pluronic Lecithin Organogel for Local Delivery of Anti-Inflammatory Drugs Frankum James, Ramsay Dale, Das Nandita G, Das Sudip K Mar/Apr 2004 101-105 Buy
Bioavailability of Promethazine in a Topical Pluronic Lecithin Organogel: A Pilot Study Glisson James K, Wood Rebecca L, Kyle Patrick B, Cleary John D May/Jun 2005 242-246 Buy
Viscosity-Increasing Agents for Aqueous Systems, Featured Excipient: Allen Loyd V Jr Nov/Dec 1999 479 Buy
The Use of Pluronic Lecithin Organogels in the Transdermal Delivery of Drugs Bramwell Bethany L, Williams LaVonn A Jan/Feb 2012 62-63 Buy