Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases

Author(s):  Allen Loyd V Jr

Issue:  Jul/Aug 2021 - Volume 25, Number 4
View All Articles in Issue

Abstract:  The selection of a rectal suppository base can be critical for proper compounding, storage, administration, and release of the drug for the patient. In this article, a number of different characteristics are discussed, as well as potential compatibility and stability issues. Also, a number of example bases are presented and discussed.

Related Keywords: Loyd V. Allen Jr., PhD, RPh, rectal suppositories, rectal suppository bases, drug availability, drug release, drug solubility, excipients, melting point, water-soluble bases, fatty bases, solutions, suspensions, cocoa butter, polymorphism, incompatibilities, hydrogenated vegetable oil bases, compatibility, polyethylene glycols, glycerin water bases, gelatin bases, poloxamers

Related Categories: EXCIPIENTS, STABILITIES, COMPATIBILITIES, DOSAGE FORMS/DRUG CARRIERS

Purchase this article for download in electronic PDF format from IJPC at for $35 at:
http://www.ijpc.com/Products/ProductAddToCart.cfm?PID=4941

Search the entire IJPC archive by keyword, topic, or issue at:
http://ijpc.com/Products