Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of all issues and individual articles published by the Journal since 1997.

Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases

Author(s):  Allen Loyd V Jr

Issue:  Jul/Aug 2021 - Volume 25, Number 4
View All Articles in Issue

Page(s):  304-309

Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 1
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 2
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 3
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 4
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 5
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 6

Download in electronic PDF format for $75

Abstract:  The selection of a rectal suppository base can be critical for proper compounding, storage, administration, and release of the drug for the patient. In this article, a number of different characteristics are discussed, as well as potential compatibility and stability issues. Also, a number of example bases are presented and discussed.

Related Keywords: rectal suppositories, rectal suppository bases, drug availability, drug release, drug solubility, excipients, melting point, water-soluble bases, fatty bases, solutions, suspensions, cocoa butter, polymorphism, incompatibilities, hydrogenated vegetable oil bases, compatibility, polyethylene glycols, glycerin water bases, gelatin bases, poloxamers

Related Categories: EXCIPIENTS, STABILITIES, COMPATIBILITIES, DOSAGE FORMS/DRUG CARRIERS

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases
Allen Loyd V Jr
Jul/Aug 2021
Pg. 304-309

Compounding Pearls -- Wound Care: Base Selection
Riepl Mike
Mar/Apr 2020
Pg. 98-102

Basics: Considerations and Background Information for Counseling Patients Using Compounded Suppositories
Allen Loyd V Jr
Jan/Feb 2022
Pg. 34-38

Isoniazid Release from Suppositories Compounded with Selected Bases
Hudson Kristofer C
, Asbill C Scott, Webster Andrew A
Sep/Oct 2007
Pg. 433-437

Compounded Suppositories and Pharmaceutical Care
Duncan-Hewitt Wendy
, Rains John
Mar/Apr 1997
Pg. 93-99

Drug-release Assessment of Compounded Topical Nifedipine and Diltiazem in Commonly Used Bases for Wound Healing
Teimouri Arezou
, Yeung Pollen, Agu Remigius U
Nov/Dec 2020
Pg. 501-508

Compounding in the Pharmacy Curriculum: Beyond the Basics
Hinkle Amanda R
, Newton Gail D
May/Jun 2004
Pg. 181-185

Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 11: Drug Tastes: Innate, Induced, and Improved
Allen Loyd V Jr
Sep/Oct 2021
Pg. 396-400

Ondansetron Suppositories: Extemporaneous Preparation, Drug Release, Stability and Flux through Rabbit Rectal Membrane
Tenjarla Srini N
, Ward Earl S, Fox Janet L
Jan/Feb 1998
Pg. 83-88

Preparation and Evaluation of Sustained Drug Release from Pluronic Polyol Rectal Suppositories
Anderson Derick
, Amiji Mansoor M
May/Jun 2001
Pg. 234-237

Basics: Hollow-type Suppositories
Allen Loyd V Jr
Jul/Aug 2022
Pg. 302-307

Topical Oil-in-Water Cream Bases, Featured Excipient:
Allen Loyd V Jr
Jul/Aug 2002
Pg. 303-304

Progesterone Vaginal Suppositories (Fatty Acid Base)
Allen Loyd V Jr
Jan/Feb 1998
Pg. 65

Progesterone Vaginal Suppositories (Fatty Acid Base)
Allen Loyd V Jr
Jan/Feb 2024
Pg. 63

Formulation and In Vitro Evaluation of a Ramipril Entrapped in a Microsponge-based Drug-delivery System
Taghi Hassanien Sagban
, Abdulbaqi Mustafa R, Samein Laith Hamza, Rahmani Maha H Philip
Jul/Aug 2023
Pg. 340-346

Basics: Excipients Used in Nonsterile Compounding, Part 1
Allen Loyd V Jr
Jul/Aug 2019
Pg. 305-311

Basics of Compounding: Compounding Suppositories: Part I - Theoretical Considerations
Allen Loyd V Jr
Jul/Aug 2000
Pg. 289-293

Ketorolac tromethamine and Ketoprofen suppositories: release profiles and bioavailability of cocoa butter base formula in rabbits
Zia Hossein
, Rashed Suzette F, Quadir Mohammed, Needham Thomas E, Squillante Emilio
Sep/Oct 1998
Pg. 390-393

In Vitro Evaluation of Extemporaneously Compounded Immediate-release Capsules with Premixed Excipients, Based on the Biopharmaceutics Classification System (BCS) of the Drugs
Pinheiro Vanessa A
, Danopoulos Panagiota, Demirdjian Lara, Nogueira Rodrigo J L, Dubois Fanny
Sep/Oct 2013
Pg. 424-431

Sterile Basics: Pharmaceutical Waters Used in Sterile and Nonsterile Compounding
Allen Loyd V Jr
Sep/Oct 2019
Pg. 399-402

Return to Top