Abstract

Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases

Author(s): Allen Loyd V Jr

Issue: Jul/Aug 2021 - Volume 25, Number 4

Page(s): 304-309

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  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 1
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 2
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 3
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 4
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 5
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases Page 6

Abstract

The selection of a rectal suppository base can be critical for proper compounding, storage, administration, and release of the drug for the patient. In this article, a number of different characteristics are discussed, as well as potential compatibility and stability issues. Also, a number of example bases are presented and discussed.

Related Keywords

  • rectal suppositories
  • rectal suppository bases
  • drug availability
  • drug release
  • drug solubility
  • excipients
  • melting point
  • water-soluble bases
  • fatty bases
  • solutions
  • suspensions
  • cocoa butter
  • polymorphism
  • incompatibilities
  • hydrogenated vegetable oil bases
  • compatibility
  • polyethylene glycols
  • glycerin water bases
  • gelatin bases
  • poloxamers

Related Categories

  • EXCIPIENTS
  • STABILITIES, COMPATIBILITIES
  • DOSAGE FORMS/DRUG CARRIERS

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