Abstract
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases
Author(s): Allen Loyd V Jr
Issue: Jul/Aug 2021 - Volume 25, Number 4
Page(s): 304-309
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Abstract
The selection of a rectal suppository base can be critical for proper compounding, storage, administration, and release of the drug for the patient. In this article, a number of different characteristics are discussed, as well as potential compatibility and stability issues. Also, a number of example bases are presented and discussed.
Related Keywords
- rectal suppositories
- rectal suppository bases
- drug availability
- drug release
- drug solubility
- excipients
- melting point
- water-soluble bases
- fatty bases
- solutions
- suspensions
- cocoa butter
- polymorphism
- incompatibilities
- hydrogenated vegetable oil bases
- compatibility
- polyethylene glycols
- glycerin water bases
- gelatin bases
- poloxamers
Related Categories
- EXCIPIENTS
- STABILITIES, COMPATIBILITIES
- DOSAGE FORMS/DRUG CARRIERS
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