Quantitation of Testosterone Propionate in an Injection Using High Performance Liquid Chromatography

Author(s):  Gupta Vishnu D

Issue:  Mar/Apr 1999 - Compounding for Men's Health
View All Articles in Issue

Abstract:  A high-performance liquid chromatography assay method for the quantitation of testosterone propionate in an injection has been developed. The assay method is very simple, precise and accurate, with a percent relative standard deviation of 1.3 based on five injections. The benzyl alcohol (the preservative) and sesame oil (the vehicle) did not interfere with the assay procedure. The extraction procedure is very simple compared with a tedious and time-consuming method recommended in the USP-NF. The other similar compounds, testosterone, methyltestosterone, testosterone cypionate and testosterone enanthate, did not interfere with the assay method. Hence, the method developed is specific for this drug, versus the USP-NF method, which is nonspecific.

Related Keywords: high-performance liquid chromatography, HPLC, methyltestosterone, testosterone cypionate, testosterone enanthate

Related Categories: HRT, PEER-REVIEWED

Purchase this article for download in electronic PDF format from IJPC at for $35 at:
http://www.ijpc.com/Products/ProductAddToCart.cfm?PID=686

Search the entire IJPC archive by keyword, topic, or issue at:
http://ijpc.com/Products