Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Physical characteristics of selected over-the-counter medications

Author(s):  Al-Achi Antoine, Shipp Shawnte

Issue:  Jan/Feb 2005 - Sterile Preparations
View All Articles in Issue

Abstract:  The physical characteristics of over-the-counter medications may be useful to the compounding pharmacist in preparing dosage forms by serving as physical limits for the basis of choice of vehicles and supporting ingredients for formulations. In this study, three bottles of 16 different products were tested for their specific gravity, pH, surface tension, and rheological properties. All products tested were heavier than water, with the exception of the lotions. The pH value varied greatly among the products, and the lotions were neutral to slightly acidic; the other preparations were acidic with the exception of Dulcolax and Maalox, which showed a basic pH. Aqueous solutions had a surface tension very close in value to water; all other products that were tested exhibited lower surface tension than water. The viscosity of the products varied greatly; lotions and suspensions demonstrated shear-thinning properties of either plastic or pseudoplastic type; and all solutions had low viscosity similar to that of water, except for Children's Dimetapp and Vicks NyQuil, which showed a somewhat higher viscosity than water.

Related Keywords: Antoine Al-Achi, PhD, Shawnte Shipp, nonprescription medications, OTC medications


Printer-Friendly Version

Download in electronic PDF format for $65

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Veterinary Transdermal Medications: A to Z Davidson Gigi S Mar/Apr 2003 106-113 Buy
Physical characteristics of selected over-the-counter medications Al-Achi Antoine, Shipp Shawnte Jan/Feb 2005 75-81 Buy
Rheologic Profile, Specific Gravity, Surface Tension, and pH of Fifteen Over-the-Counter Preparations Al-Achi Antoine, Baghat Tushar, Chukwubeze Onah, Dembla Ishwin May/Jun 2007 252-258 Buy
Acacia and Mineral Oil Emulsion NF Al-Achi Antoine, Mosley Anita, Patlolla Swapna Jan/Feb 2006 44 Buy
Preparation and Characterization of a Compounded Aqueous Human Insulin Suspension Al-Achi Antoine, Parekh Bhavita Nov/Dec 2004 492-495 Buy
Quality-Control Analytical Methods: Determination of Tapped Bulk Volume for Compounded Prescriptions Al-Achi Antoine, Siddoju Srujana May/Jun 2005 207 Buy
Capsule Machine Validation Al-Achi Antoine, McGreggor Tysheon, Jaligama Shreelekha, Friday Kafi, Alyami Hussain Jan/Feb 2022 58-64 Buy
Evaluating Transdermal Medication Forms for Veterinary Patients, Part 1 Davidson Gigi S Mar/Apr 2001 95-96 Buy
Stability of Vancomycin HCl in MEDICATION CASSETTE Reservoirs Allen Loyd V Jr, Stiles M Lou Mar/Apr 1997 123-124 Buy
Evaluating Transdermals Medication Froms for Veterinary Patients, Part 2 Davidson Gigi S May/Jun 2001 214-215 Buy
Particle Measuring Systems - USP <797> Environmental Monitoring Solutions