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Veterinary Transdermal Medications: A to Z

Author(s):  Davidson Gigi S

Issue:  Mar/Apr 2003 - Terrorism
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Page(s):  106-113

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Abstract:  Transdermal medication delivery for veterinary patients (especially cats) is a landmark in veterinary pharmacotherapy. Many medications can be administered transdermally to veterinary patients, but some drugs are not suitable for this dosage form. This article focuses on general considerations (bioavailability, metabolic fate, effective concentrations at the site of action, drugs with a narrow therapeutic index, diagnostic agents, glucocorticoids and risks to the caregiver), the regulatory environment for transdermal compounding, current evidence supporting transdermal dosing and collecting clinical evidence of safety and efficacy. A table containing information about veterinary drugs that can be considered for transdermal therapy is included. In summary, pharmacists and veterinarians must collaborate to decide when compounded transdermal therapy is appropriate, safe and effective. Regardless of the likelihood of clinical success from using a compounded transdermal medication, the safety of the caregiver must be the highest priority.

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