Abstract

Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 7: Microbial Contamination Risk Levels, 12-Hour Use, and Immediate Use

Author(s): Allen Loyd V Jr, Okeke Claudia C

Issue: May/Jun 2008 - Pain Management

Page(s): 252-257

Download in electronic PDF format for $75

Abstract

This articles discusses the types of contamination that may occur when compounding personnel prepare, handle, or store sterile preparations, as discussed in United States Pharmacopeia Chapter <797> Pharmaceutical Compounding—Sterile Preparations. Contamination may be microbial, physical, or chemical, and all these are possible when sterile preparations are made. Microbial contamination may be fungal or bacterial. The most frequently identified microbial organisms in sterile preparations are spores and endotoxins. Chemical and physical contamination includes foreign objects, chemicals, physical matter, nonsterile components or objects, and airborne particles, objects, or matter from environments with uncontrolled air quality. Thorough knowledge of the possible sources of contamination can help in implementing the steps and processes to avoid contamination. The purpose of this article is to review the contamination risk level categories as discussed in Chapter <797>.

Related Keywords

Related Categories

Printer-Friendly Version

Related Articles from IJPC

Issue/Page View/Buy	Title/Author (Click for Abstract / Details / Purchase)
Sep/Oct 2007 Pg. 404-410	Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 3: Risk Levels Author(s): Allen Loyd V Jr, Okeke Claudia C
May/Jun 2008 Pg. 252-257	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 7: Microbial Contamination Risk Levels, 12-Hour Use, and Immediate Use Author(s): Allen Loyd V Jr, Okeke Claudia C
Mar/Apr 2020 Pg. 92	PreScription: Formal Appeals to United States Pharmacopeia Regarding USP Chapters <795>,<797>, and <825>: Part 1 Author(s): Allen Loyd V Jr
Nov/Dec 2021 Pg. 491-496	Basics of Sterile Compounding: Intravenous Admixture Preparation, Part 12: United States Pharmacopeia Chapters Referenced in the Current United States Pharmacopeia Chapter <797> Pharmaceutical Compounding -- Sterile Preparations Author(s): Allen Loyd V Jr
May/Jun 2020 Pg. 180	PreScription: Formal Appeals to United States Pharmacopeia Regarding USP Chapters <795>, <797>, and <825>: Part 2 Author(s): Allen Loyd V Jr
Mar/Apr 2012 Pg. 146-150	Basics of Compounding: Implementing United States Pharmacopeia Chapter <1163> Quality Assurance in Pharmaceutical Compounding, Part 1 Author(s): Allen Loyd V Jr
Sep/Oct 2008 Pg. 440-443	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 9: Immediate-Use Compounded Sterile Preparations Author(s): Allen Loyd V Jr, Okeke Claudia C
Mar/Apr 2021 Pg. 115-124	Quality Control: Minor Chapters, Major Impacts: What United States Pharmacopeia Chapters <51>, <61>, <62>, and <1207> Mean for Your Compounding Practice Author(s): Kelley Brian
Jan/Feb 2012 Pg. 64-68	Basics of Compounding: Implementing United States Pharmacopeia Chapter <795> Pharmaceutical Compounding–Nonsterile Preparations, Part 4 Author(s): Allen Loyd V Jr
Jul/Aug 2011 Pg. 328-331	Basics of Compounding: Implementing United States Pharmacopeia Chapter <795> Pharmaceutical Compounding--Nonsterile Preparations, Part 1 Author(s): Allen Loyd V Jr
Nov/Dec 2011 Pg. 488-496	Basics of Compounding: Implementing United States Pharmacopeia Chapter <795> Pharmaceutical Compounding--Nonsterile Preparations, Part 3 Author(s): Allen Loyd V Jr
Mar/Apr 2008 Pg. 136-144	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 6: 2008 Revisions to Chapter <797> Author(s): Allen Loyd V Jr, Okeke Claudia C
Jul/Aug 2007 Pg. 302-305	Update on the Proposed Revision Process for United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations Author(s): Okeke Claudia C
Sep/Oct 2011 Pg. 408-414	Basics of Compounding: Implementing United States Pharmacopeia Chapter <795> Pharmaceutical Compounding--Nonsterile Preparations, Part 2 Author(s): Allen Loyd V Jr
May/Jun 2008 Pg. 216-229	Microbial Air-Sampling Equipment, Part 1: Meeting United States Pharmacopeia Chapter <797> Standards Author(s): Kastango Eric S
Nov/Dec 2007 Pg. 492-499	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 4: Considerations in Selection and Use of Disinfectants and Antiseptics Author(s): Allen Loyd V Jr, Okeke Claudia C
May/Jun 2009 Pg. 234-238	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 13: Environmental Quality and Control Author(s): Allen Loyd V Jr, Okeke Claudia C
Jul/Aug 2009 Pg. 322-329	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 14: Environmental Quality and Control (Continued) Author(s): Okeke Claudia C, Allen Loyd V Jr
Jan/Feb 2008 Pg. 54-60	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 5: Verification of Accuracy, Sterility, and Sterilization of Compounded Preparations Author(s): Allen Loyd V Jr, Okeke Claudia C
Jul/Aug 2008 Pg. 344-353	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 8; Stability and Beyond-Use Dating Author(s): Allen Loyd V Jr, Okeke Claudia C