Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP

Author(s):  Allen Loyd V Jr

Issue:  May/Jun 2003 - Diabetes and Wound Care
View All Articles in Issue

Page(s):  180-183

The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP Page 1
The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP Page 2
The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP Page 3
The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP Page 4

Download in electronic PDF format for $65

Abstract:  A decade ago, Pluronic lecithin organogel was developed by Marty Jones. His colleague Lawson Kloesel suggested adding Pluronic F127 to stabilize the original formula. In this interview, Jones describes the process of creating this base for transdermal preparations and explains how and why it is effective. Topics discussed include the way Pluronic lecithin organogel was developed, its mechanism of action, ways the first formulation was improved, its clinical evaluation, steps in defining its uses, drugs not appropriate for use in this vehicle, storage or preparations and its future as a transdermal vehicle. Sample formulations for transdermal compounds using Pluronic lecithin organogel are provided, including Ketoprofen 10% in PLO, ABHR in PLO, Ketamine Hydrochloride 10%, Gabapentin 6%, Clonidine Hydrochloride 0.2% in PLO, and Methimazole 5 mg/0.l mL in PLO (Veterinary Formulation).

Related Keywords: ABHR in PLO, Ketamine HCl 10%, gabapentin 6%, clonidine HCl 0.2% in PLO, formulation for, Ketoprofen 10% in PLO, formulation for, Methimazole 5 mg/0.1 mL in PLO (veterinary formulation), PLO, history of, PLO, in transdermal gels, formulations for, Pluronic lecithin organogel, history of

Related Categories: DIABETES, HISTORY, PAIN MANAGEMENT

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
The History of Pluronic Lecithin Organogel: An Interview With Marty Jones, BSPharm, FACA, FIACP
Allen Loyd V Jr
May/Jun 2003
Pg. 180-183

Veterinary Transdermal Medications: A to Z
Davidson Gigi S
Mar/Apr 2003
Pg. 106-113

Compounding in the Pharmacy Curriculum: Beyond the Basics
Hinkle Amanda R
, Newton Gail D
May/Jun 2004
Pg. 181-185

Clonidine HCl 0.2%/Gabapentin 6%/Ketamine HCl 10% in Pluronic Lecithin Organogel (PLO)
Hinkle Amanda R
, Newton Gail D
May/Jun 2004
Pg. 185

Clonidine HCl 0.2%, Gabapentin 6%, and Ketamine HCl 10% in a Pluronic Lecithin Organogel (PLO)
Allen Loyd V Jr
Jan/Feb 2002
Pg. 42

Ketamine HCl 10%, Gabapentin 6%, Baclofen 2%, Amitriptyline HCl 2% and Clonidine HCl 0.1% in PLO
Allen Loyd V Jr
Mar/Apr 2000
Pg. 133

Capsaicin 0.075%, Ketamine HCl 2% and Ketoprofen 10% in PLO
Allen Loyd V Jr
Jan/Feb 2000
Pg. 51

Ketamine HCl 5% and Ketoprofen 5% in PLO
Allen Loyd V Jr
Sep/Oct 2004
Pg. 389

BHR in PLO Gel (Benadryl, Haldol, and Reglan in Pluronic Lecithin Organogel)
Allen Loyd V Jr
Jul/Aug 2021
Pg. 322

Dexamethasone 1.2%, Lorazepam 0.1%, Haloperidol 0.1%, Diphenhydramine HCl 2.4% and Metoclopramide HCl 2.4% in PLO
Allen Loyd V Jr
Jul/Aug 2000
Pg. 297

Particle Measuring Systems - USP <797> Environmental Monitoring Solutions