Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together

Author(s):  McElhiney Linda F

Issue:  Jul/Aug 2010 - Sterile Compounding
View All Articles in Issue

Page(s):  270-274

Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together Page 1
Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together Page 2
Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together Page 3
Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together Page 4
Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together Page 5

Download in electronic PDF format for $75

Abstract:  With the development of new treatment options and reported side effects with the use of silver nitrate ophthalmic solution, the drug manufacturers discontinued production of the silver nitrate ophthalmic solution in the mid 1990s. On December 9, 2009, the U.S. Food and Drug Administration announced that the erythromycin ophthalmic ointment 1-gram tubes were commercially available again and production by the manufacturer was expected to meet the historical demands. Hospitals could expect to replenish their inventory reserves after the first quarter of 2010. However, manufacturer backorders have been increasing due to a variety of factors. If a hospital has a compounding laboratory, it is possible to prepare erythromycin ophthalmic ointment according to the United States Pharmacopeia Chapter <797> standards. Since the commercial product has been available for decades without any major shortages until 2009, there isn’t any published compounding information on how to prepare the ointment. This article discusses t

Related Keywords: Linda F. McElhiney, PharmD, RPh, FIACP, FASHP, gonococcal ophthalmia neonatorum, neonatal blindness, newborns, erythromycin ophthalmic ointment, prophylaxis, drug shortage, treatment alternatives, topical antibiotic, intraocular antimicrobial, ocular administration, eye infection, formulation

Related Categories: FORMULATIONS, OPHTHALMICS, PEDIATRICS, STERILE PREPARATIONS, DOSAGE FORMS/DRUG CARRIERS, INFECTIOUS DISEASE

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Developing an Erythromycin Ophthalmic Ointment: Putting the Puzzle Pieces Together
McElhiney Linda F
Jul/Aug 2010
Pg. 270-274

Compounding for the Effects of Weapons of Mass Destruction
Sammarco Domenic A
Jan/Feb 2003
Pg. 10-15

View Sample
Basics of Sterile Compounding: Ophthalmic Preparations, Part 2: Suspensions and Ointments
Allen Loyd V Jr
Nov/Dec 2016
Pg. 495-500

Erythromycin 1% and Neomycin Sulfate Ointment
Allen Loyd V Jr
Mar/Apr 2008
Pg. 153

Ointment Vehicles, Featured Excipient:
Allen Loyd V Jr
Mar/Apr 2001
Pg. 145-146

Dexamethasone 0.1%, Neomycin 0.35%, and Polymixin 10,000 Units/g Ophthalmic Ointment
Allen Loyd V Jr
May/Jun 2016
Pg. 228

Dexamethasone, Neomycin, and Polymyxin Ophthalmic Ointment
Allen Loyd V Jr
Jan/Feb 2016
Pg. 51

Erythromycin 50-mg/mL Injection
Allen Loyd V Jr
Jan/Feb 2015
Pg. 64

Tetracycline HCl 1% Ophthalmic Ointment
Allen Loyd V Jr
May/Jun 2001
Pg. 212

Erythromycin and Dexamethasone Ophthalmic Solution
Allen Loyd V Jr
Nov/Dec 2002
Pg. 452

Dexamethasone Phosphate 0.05% Ophthalmic Ointment
Allen Loyd V Jr
May/Jun 2003
Pg. 215

Bacitracin 500-U/g Ophthalmic Ointment
Allen Loyd V Jr
Nov/Dec 2003
Pg. 467

I See Colors: Using Vital Dyes in Diagnosing Ophthalmic Disease
McElhiney Linda F
May/Jun 2012
Pg. 190-195

Three Fortified Ophthalmic Solutions: Amikacin 5% Ophthalmic Solution; Ceftazidime 5% Ophthalmic Solution; Vancomycin 5% Ophthalmic Solution
Allen Loyd V Jr
Sep/Oct 2010
Pg. 421

Basics of Sterile Compounding: Ophthalmic Preparations, Part 1: Ophthalmic Solutions
Allen Loyd V Jr
Sep/Oct 2016
Pg. 399-404

Medications Discontinued in the United States
Ashworth Lisa D
Nov/Dec 2002
Pg. 441-442

Glucose 40% Ophthalmic Ointment
Allen Loyd V Jr
May/Jun 1998
Pg. 230

Treating Inner Ear Disorders with Intratympanic Drug Administration
McElhiney Linda F
Jul/Aug 2011
Pg. 302-307

PreScription: Discontinued Drugs and Drug Shortages
Allen Loyd V Jr
Mar/Apr 2011
Pg. 92

PreScription: The International Academy of Compounding Pharmacists Remembers Evelyn Timmons, RPh, FIACP, and George Roentsch, RPh, FIACP
Karolchyk Scott
Jan/Feb 2012
Pg. 4

View Sample
Return to Top