Sterilization and Depyrogenation Principles and Methods
Author(s): Akers Michael J
Issue: Jul/Aug 1999 - Compounding Parenteral Products
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Abstract: This article highlights the most important principles and applications of current practices for sterilization and depyrogenation of materials, equipment and products that must be free from microbial and pyrogenic contamination. The author, affiliated with Lilly Research Laboratories, discusses the four basic methods for achieving sterilization: heat, gas, radiation and filtration. He also discusses emerging methods (ozone, gas plasma and white light).
Related Keywords: autoclave, cobalt-60, cold spot, depyrogenation, dry-heat sterilization, endotoxins, ethylene oxide, filtration sterilization, gamma radiation, gas, gas plasma, gaseous chemical sterilization, hydrogen peroxide, ionizing sterilization, microbial life, moist-heat sterilization, ozone, peracetic acid, pyrogens, radiation sterilization, sterility, sterilization, ultraviolet light, white light
Related Categories: STERILE PREPARATIONS, SUPPORT, UNITED STATES PHARMACOPEIA CONVENTIONS
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