Abstract

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations

Author(s): Allen Loyd V Jr

Issue: May/Jun 1998 - Compounding Ophthalmics

Page(s): 192-195

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Abstract

A number of factors are involved in the selection of a preservative for ophthalmics. This discussion covers physicochemical characteristics, uniqueness and incompatibilities of common preservatives (benzalkonium chloride, benzethonium chloride, chlorobutanol, the parabens, mercurial compounds and testing of preservative effectiveness. A table provides information regarding common preservatives used in ophthalmic, otic and nasal products. A sidebar provides a primer on sterilization and sterility testing.

Related Keywords

  • Thimerosal

Related Categories

  • OPHTHALMICS
  • STERILE PREPARATIONS
  • QUALITY CONTROL
  • UNITED STATES PHARMACOPEIA CONVENTIONS

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