International Journal of Pharmaceutical Compounding

A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

LEARN MORE

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations

Author(s): Allen Loyd V Jr

Issue: May/Jun 1998 - Compounding Ophthalmics
View All Articles in Issue

Page(s): 192-195

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations Page 1

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations Page 2

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations Page 3

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations Page 4

Download in electronic PDF format for $75

Abstract: A number of factors are involved in the selection of a preservative for ophthalmics. This discussion covers physicochemical characteristics, uniqueness and incompatibilities of common preservatives (benzalkonium chloride, benzethonium chloride, chlorobutanol, the parabens, mercurial compounds and testing of preservative effectiveness. A table provides information regarding common preservatives used in ophthalmic, otic and nasal products. A sidebar provides a primer on sterilization and sterility testing.

Related Keywords: Thimerosal

Related Categories: OPHTHALMICS, STERILE PREPARATIONS, QUALITY CONTROL, UNITED STATES PHARMACOPEIA CONVENTIONS

Printer-Friendly Version

Title/Author (Click for Abstract / Details / Purchase)	Issue/Page View/Buy
Related Articles from IJPC
Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations Allen Loyd V Jr	May/Jun 1998 Pg. 192-195
Quality Control Analytical Methods: End-preparation Assessments and Tests for Compounded Sterile Preparations McElhiney Linda F	Jul/Aug 2013 Pg. 307-311
Sterile Basics of Compounding: Methods of Sterilization and Depyrogenation Allen Loyd V Jr	Mar/Apr 2022 Pg. 129-136
Sterilization and Depyrogenation Principles and Methods Akers Michael J	Jul/Aug 1999 Pg. 263-269
Basics of Sterile Compounding: Intravenous Admixture Preparation, Part 12: United States Pharmacopeia Chapters Referenced in the Current United States Pharmacopeia Chapter <797> Pharmaceutical Compounding -- Sterile Preparations Allen Loyd V Jr	Nov/Dec 2021 Pg. 491-496
Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 5: Verification of Accuracy, Sterility, and Sterilization of Compounded Preparations Allen Loyd V Jr, Okeke Claudia C	Jan/Feb 2008 Pg. 54-60
Standard Operating Procedure: Sterility Test for Ophthalmic Solutions Allen Loyd V Jr	May/Jun 2006 Pg. 218
Summary of Quality-Control Testing for Sterile and Nonsterile Compounded Preparations, Part 2: Microbiological Testing Allen Loyd V Jr	Jul/Aug 2019 Pg. 299-303
Quality Control: Rapid Sterility Testing for Compounding Pharmacies Taylor Andrew	Jul/Aug 2020 Pg. 299-303
USP Chapter <797>: Practical Solutions for Microbiology, Sterility, and Pyrogen Testing Caputo Ross A, Huffman Anne, Reich Robert	Jan/Feb 2005 Pg. 11-13
Basics of Sterile Compounding: Ophthalmic Preparations, Part 2: Suspensions and Ointments Allen Loyd V Jr	Nov/Dec 2016 Pg. 495-500
Quality Control Analytical Methods: The Quality of Sterility Testing McGuire Jason, Kupiec Thomas C	Jan/Feb 2007 Pg. 52-55
Quality-Control Analytical Methods: A Discussion of United States Pharmacopeia Chapter <71> Sterility Tests Kupiec Thomas C	Sep/Oct 2007 Pg. 400-403
Using Hospital Laboratory Services to Perform Quality-control Testing on Compounded Preparations Donnelly Ronald F	Sep/Oct 2015 Pg. 383-386
Basics of Sterile Compounding: Ophthalmic Preparations, Part 1: Ophthalmic Solutions Allen Loyd V Jr	Sep/Oct 2016 Pg. 399-404
Microbiologic Testing for 503A Sterile-Compounding Pharmacies Mixon William, Roth Abby	May/Jun 2017 Pg. 193-203
Basics of Sterile Compounding: Sterilization Methods in Sterile Product Manufacturing Akers Michael J	Mar/Apr 2015 Pg. 127-138
Basics of Compounding: Application of the United States Pharmacopeia Bacterial Endotoxins Test to Compounded Sterile Preparations Dawson Michael F	Jan/Feb 2006 Pg. 36-39
Quality Control: Microbial Limit Tests for Nonsterile Pharmaceuticals, Part 2 Vu Nicole, Lou Jessica R, Kupiec Thomas C	Jul/Aug 2014 Pg. 305-310
Quality-Control Analytical Methods: Microbial Testing Aspects of USP <797> for Compounded Sterile Preparations Kupiec Thomas C	Jan/Feb 2005 Pg. 47-49
Return to Top