Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Topical Treatment of Cutaneous Leishmaniasis in Israel, Part 3

Author(s):  Zur Eyal

Issue:  Sep/Oct 2019 - Volume 23, Number 5
View All Articles in Issue

Abstract:  Cutaneous leishmaniasis is the most common form of leishmaniasis with global incidence of about 1.5 million cases annually. The disease is endemic in Israel and caused by two types, leishmania major and leishmania tropica. The two types of cutaneous leishmaniasis in Israel are not life threatening, but the multiple skin lesions developed from the contaminated sandfly bites cause significant damage to the quality of life for a few months in patients with leishmania major and sometimes for more than a year in patients with leishmania tropica. Topical treatment for this localized skin disease is very attractive although only one medication is registered in Israel (15% paromomycin +12% methylbenzethonium chloride ointment) for the topical treatment of leishmania major. Two significant disadvantages characterize this topical medication, 1) relatively low efficacy and 2) significant irritation and pain. This article represents part 3 of a 3-part article on the topic of cutaneous leishmaniasis. Part 1 discussed the treatment option of amphotericin-B liposomal gel, part 2 discussed the treatment option of paromomycin sulfate liposomal gel, and this final part (3) discusses the treatment option of photodynamic therapy.

Related Keywords: Eyal Zur, BScPharm, RPh, MBA, cutaneous leishmaniasis, leishmania major, leishmania tropica, Israel, topical preparations, photodynamic therapy, daylight activation, photosensitizer, 5-aminolevulinic acid hydrochloride, formulations, amphotericin B liposomal gel, paromomycin sulfate liposomal gel


Printer-Friendly Version

Download in electronic PDF format for $45

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Topical Treatment of Cutaneous Leishmaniasis in Israel, Part 3 Zur Eyal Sep/Oct 2019 366-375 Buy
Topical Treatment of Cutaneous Leishmaniasis in Israel, Part 2 Zur Eyal Jul/Aug 2019 288-293 Buy
Topical Treatment of Cutaneous Leishmaniasis in Israel, Part 1 Zur Eyal May/Jun 2019 200-207 Buy
Treatment of Dermatologic Adverse Events Induced by Oncological Treatments Using Compounded Medications Zur Eyal Nov/Dec 2018 446-454 Buy
Novel Approaches to Topical Psoriasis Therapy Koyama Gregory, Liu Jenny, Scaffidi Alyse, Khazraee Maryam, Epstein Benjamin Sep/Oct 2015 357-365 Buy
Oral Viscous Sucralfate Gel for Post-procedural Treatment of Barrett's Esophagus Zur Eyal Sep/Oct 2019 376-381 Buy
PostScription: Compounding in Israel Zur Eyal May/Jun 2009 262-263 Buy
Low-dose Pilocarpine Spray to Treat Xerostomia Zur Eyal Mar/Apr 2020 104-108 Buy
Topical Treatment of Primary Focal Hyperhidrosis, Part 1 Zur Eyal Jan/Feb 2019 23-31 Buy
Infantile Hemangiomas, Part 2: Topical Treatment with Beta Blockers Zur Eyal Nov/Dec 2011 458-463 Buy
Update Your SOPs and Comply with PCAB/ACHC Standards