Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Novel Approaches to Topical Psoriasis Therapy

Author(s):  Koyama Gregory, Liu Jenny, Scaffidi Alyse, Khazraee Maryam, Epstein Benjamin

Issue:  Sep/Oct 2015 - Volume 19, Number 5
View All Articles in Issue

Abstract:  Topical corticosteroids are the cornerstone of treatment for the majority of psoriasis patients. However, potential side effects of topical corticosteroids (i.e., cutaneous atrophy, telangiectasias, hypothalamic-pituitary axis suppression), coupled with the complex pathophysiology of psoriasis and the individual needs/preferences of psoriasis patients, represent a few of the limitations associated with topical corticosteroid monotherapy. While the combination of some agents with varying mechanisms of action has proven to be an effective strategy for improving efficacy and reducing concomitant drug application, others have displayed less efficacy, harm, and/or reduced cost-effectiveness. The purpose of this article is to review novel topical therapeutic combinations for the management of psoriasis and explore the role compounding pharmacies can have in providing healthcare providers and patients with effective and affordable alternative psoriasis therapies.

Related Keywords: Gregory Koyama, PharmD, Jenny Liu, PharmD, Alyse Scaffidi, PharmD, Maryam Khazraee, PharmD, Benjamin Epstein, PharmD, BCPS, plaque psoriasis, immune-modulated keratinocyte hyperproliferation, skin disorders, topical preparations, drug combination therapy, topical corticosteroids, anti-inflammatory therapy, inflammation, adverse effects, topical vitamin D3 analogues, calcipotriene, calcipotriol, topical retinoids, retinoic acids, tazarotene, topical calcineurin inhibitors, tacrolimus, topical salicylic acid, keratolytic, topical anthralin, skin irritation, topical urea, drug safety, topical methotrexate, folic acid antagonist, individualized therapy, patient adherence, drug costs


Printer-Friendly Version

Download in electronic PDF format for $45

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Novel Approaches to Topical Psoriasis Therapy Koyama Gregory, Liu Jenny, Scaffidi Alyse, Khazraee Maryam, Epstein Benjamin Sep/Oct 2015 357-365 Buy
Incorporating Quality Assurance in Pharmaceutical Compounding-related Courses in the PharmD Curricula Hossain Mohammad Faisal, Levesque Dan, Frye John, Rashid Mamoon Jul/Aug 2020 322-326 Buy
Compounding for Diabetic Patients:An Interview with Paul Lofholm, PharmD Allen Loyd V Jr Nov/Dec 1997 381-385 Buy
Safe Cytotoxic Drug Preparation Using a Closed-system Transfer Device: Technical and Practical Evaluation of a New Device (Vialshield/Texium) Comparatively to a Reference One (Phaseal) Garrigue Philippe, Montana Marc, Ventre Christophe, Savry Amadine, Gauthier-Villano Laurence, Pisano Pascale, Pourroy Bertrand Mar/Apr 2016 148-154 Buy
In Vitro Permeability, Irritability, and Release Evaluation of Commonly Used Topical Diclofenac Gel Preparations (1%, 5%, and 10%) Kohan Hamed Gilzad, Baker David M, Sani Shabnam, Bielecki-Wilken Kathleen A, Ramirez Alfonso Mar/Apr 2021 146-155 Buy
Current Topical Treatments in Wound Healing - Part 1 Helmke Christopher D Jul/Aug 2004 269-274 Buy
Management of Psoriasis with a XemaTop Topical Compounded Formula: A Case Report Jones Nat, Carvalho Maria, Branvold-Herr Andrea May/Jun 2017 205-211 Buy
Chemical Stability of Morphine, Ropivacaine, and Ziconotide in Combination for Intrathecal Analgesia Robert Julien, Sorrieul Jérémy, Rossignol Elsa, Beaussart Hélène, Kieffer Hélène, Folliard Caroline, Dupoiron Denis, Devys Catherine Jul/Aug 2017 347-351 Buy
Evaluation of Dosage Form Information Provided in Pediatric Drug Trial Reports Haase Mark R, Luedtke Sherry, Robles Janie, Parker Thomas, Leff Rich, Giacoia George Jan/Feb 2009 14-18 Buy
Treatment Options for Psoriasis Williams LaVonn A, Humphreys Erica May/Jun 2011 204-213 Buy