Abstract

Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations

Author(s): Allen Loyd V Jr

Issue: May/Jun 1998 - Compounding Ophthalmics

Page(s): 192-195

Download in electronic PDF format for $75

Abstract

A number of factors are involved in the selection of a preservative for ophthalmics. This discussion covers physicochemical characteristics, uniqueness and incompatibilities of common preservatives (benzalkonium chloride, benzethonium chloride, chlorobutanol, the parabens, mercurial compounds and testing of preservative effectiveness. A table provides information regarding common preservatives used in ophthalmic, otic and nasal products. A sidebar provides a primer on sterilization and sterility testing.

Related Keywords

Related Categories

Printer-Friendly Version

Related Articles from IJPC

Issue/Page View/Buy	Title/Author (Click for Abstract / Details / Purchase)
May/Jun 1998 Pg. 192-195	Preservation, Sterilization, and Sterility Testing of Ophthalmic Preparations Author(s): Allen Loyd V Jr
Jul/Aug 2013 Pg. 307-311	Quality Control Analytical Methods: End-preparation Assessments and Tests for Compounded Sterile Preparations Author(s): McElhiney Linda F
Mar/Apr 2022 Pg. 129-136	Sterile Basics of Compounding: Methods of Sterilization and Depyrogenation Author(s): Allen Loyd V Jr
Jul/Aug 1999 Pg. 263-269	Sterilization and Depyrogenation Principles and Methods Author(s): Akers Michael J
Nov/Dec 2021 Pg. 491-496	Basics of Sterile Compounding: Intravenous Admixture Preparation, Part 12: United States Pharmacopeia Chapters Referenced in the Current United States Pharmacopeia Chapter <797> Pharmaceutical Compounding -- Sterile Preparations Author(s): Allen Loyd V Jr
Jan/Feb 2008 Pg. 54-60	Basics of Compounding: Considerations for Implementing United States Pharmacopeia Chapter <797> Pharmaceutical Compounding--Sterile Preparations, Part 5: Verification of Accuracy, Sterility, and Sterilization of Compounded Preparations Author(s): Allen Loyd V Jr, Okeke Claudia C
Jul/Aug 2019 Pg. 299-303	Summary of Quality-Control Testing for Sterile and Nonsterile Compounded Preparations, Part 2: Microbiological Testing Author(s): Allen Loyd V Jr
May/Jun 2006 Pg. 218	Standard Operating Procedure: Sterility Test for Ophthalmic Solutions Author(s): Allen Loyd V Jr
Jul/Aug 2020 Pg. 299-303	Quality Control: Rapid Sterility Testing for Compounding Pharmacies Author(s): Taylor Andrew
Jan/Feb 2005 Pg. 11-13	USP Chapter <797>: Practical Solutions for Microbiology, Sterility, and Pyrogen Testing Author(s): Caputo Ross A, Huffman Anne, Reich Robert
Jan/Feb 2007 Pg. 52-55	Quality Control Analytical Methods: The Quality of Sterility Testing Author(s): McGuire Jason, Kupiec Thomas C
Sep/Oct 2007 Pg. 400-403	Quality-Control Analytical Methods: A Discussion of United States Pharmacopeia Chapter <71> Sterility Tests Author(s): Kupiec Thomas C
Nov/Dec 2016 Pg. 495-500	Basics of Sterile Compounding: Ophthalmic Preparations, Part 2: Suspensions and Ointments Author(s): Allen Loyd V Jr
Sep/Oct 2015 Pg. 383-386	Using Hospital Laboratory Services to Perform Quality-control Testing on Compounded Preparations Author(s): Donnelly Ronald F
Sep/Oct 2016 Pg. 399-404	Basics of Sterile Compounding: Ophthalmic Preparations, Part 1: Ophthalmic Solutions Author(s): Allen Loyd V Jr
May/Jun 2017 Pg. 193-203	Microbiologic Testing for 503A Sterile-Compounding Pharmacies Author(s): Mixon William, Roth Abby
Mar/Apr 2015 Pg. 127-138	Basics of Sterile Compounding: Sterilization Methods in Sterile Product Manufacturing Author(s): Akers Michael J
Jan/Feb 2006 Pg. 36-39	Basics of Compounding: Application of the United States Pharmacopeia Bacterial Endotoxins Test to Compounded Sterile Preparations Author(s): Dawson Michael F
Jul/Aug 2014 Pg. 305-310	Quality Control: Microbial Limit Tests for Nonsterile Pharmaceuticals, Part 2 Author(s): Vu Nicole, Lou Jessica R, Kupiec Thomas C
Jan/Feb 2005 Pg. 47-49	Quality-Control Analytical Methods: Microbial Testing Aspects of USP <797> for Compounded Sterile Preparations Author(s): Kupiec Thomas C