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Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers

Author(s):  Young Jennifer L, Bogner Robin H

Issue:  May/Jun 2009 - Pain Management
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Page(s):  214-217

Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 1
Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 2
Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 3
Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 4

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Abstract:  A lidocaine-releasing adhesive buccal tablet preparation was developed to treat mouth ulcers in a patient who did not tolerate magic mouthwash. The tablet, applied locally, was compressed in a manual pellet press from a powder mixture of lidocaine hydrochloride, Carbopol-934, sodium carboxymethylcellulose, polyvinylpyrrolidone K-30, and D-mannitol. With careful local administration of lidocaine from the buccal patch, several side effects of magic mouthwash can be avoided.

Related Keywords: Jennifer L. Young, PharmD, Robin H. Bogner, RPh, mouth ulcers, oral ulceration, mouth sores, lidocaine, adhesive buccal tablet, mucoadhesive cheek patch, mucous membrane, case reports, formulations, pain relief, pain control, analgesia, analgesic

Related Categories: EAR NOSE THROAT, FORMULATIONS, GASTROENTEROLOGY, PAIN MANAGEMENT, CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS

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