International Journal of Pharmaceutical Compounding

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Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers

Author(s): Young Jennifer L, Bogner Robin H

Issue: May/Jun 2009 - Pain Management
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Page(s): 214-217

Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 1

Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 2

Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 3

Case Report: Lidocaine Mucoadhesive Buccal Tablets for Local Relief of Mouth Ulcers Page 4

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Abstract: A lidocaine-releasing adhesive buccal tablet preparation was developed to treat mouth ulcers in a patient who did not tolerate magic mouthwash. The tablet, applied locally, was compressed in a manual pellet press from a powder mixture of lidocaine hydrochloride, Carbopol-934, sodium carboxymethylcellulose, polyvinylpyrrolidone K-30, and D-mannitol. With careful local administration of lidocaine from the buccal patch, several side effects of magic mouthwash can be avoided.

Related Keywords: mouth ulcers, oral ulceration, mouth sores, lidocaine, adhesive buccal tablet, mucoadhesive cheek patch, mucous membrane, case reports, formulations, pain relief, pain control, analgesia, analgesic

Related Categories: EAR NOSE THROAT, FORMULATIONS, GASTROENTEROLOGY, PAIN MANAGEMENT, CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS

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