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Abstract:  Pain caused by disorders of movement is often chronic and severe and may not be alleviated by commercially available medications. In such cases, the use of a compounded formulation can provide relief, either as sole therapy or as part of a combination treatment regimen. In this report, we review the effects of compounded analgesic preparations on chronic severe pain like that produced by arthritis, neuropathy, or postpolio syndrome. Case reports are included, formulations are presented, and two patients (one of whom, RFM III, is a coauthor of this paper) with a painful movement disorder describe their response to custom compounded therapy.

Related Keywords: Scott Brown, RPh, Brian Erickson, MD, George Muller, RPh, Susan J. Bryant-Snure, MD, Richard F. Mestayer III, MD, formulations, movement disorders, arthritis, osteoarthritis, rheumatic disorders, neuropathy, neuropathic pain, postpolio syndrome, polio, nerve pain, chronic pain, analgesic, analgesia, pain management, pain control, transdermal gel, topical preparations, intranasal administration, nasal sprays, oxytocin, hydrocodone, amitriptyline, gabapentin, ketoprofen, degenerative disk disease, inflammatory disorders, inflammation, back pain, joint pain, baclofen, clonidine, lidocaine, case reports, spinal pain, substance abuse, addiction, opioids

Related Categories: EXCIPIENTS, FORMULATIONS, PAIN MANAGEMENT, CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS, MUSCULOSKELETAL DISORDERS

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