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Case Report: The Use of Inhaled Cyclosporine to Treat Bronchiolitis Obliterans Syndrome in a Lung Transplant Patient

Author(s):  McElhiney Linda F

Issue:  Mar/Apr 2010 - Compounding for Men
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Page(s):  112-115

Case Report: The Use of Inhaled Cyclosporine to Treat Bronchiolitis Obliterans Syndrome in a Lung Transplant Patient Page 1
Case Report: The Use of Inhaled Cyclosporine to Treat Bronchiolitis Obliterans Syndrome in a Lung Transplant Patient Page 2
Case Report: The Use of Inhaled Cyclosporine to Treat Bronchiolitis Obliterans Syndrome in a Lung Transplant Patient Page 3
Case Report: The Use of Inhaled Cyclosporine to Treat Bronchiolitis Obliterans Syndrome in a Lung Transplant Patient Page 4

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Abstract:  The first lung transplantation was performed successfully in 1983 and has become a viable option for end-stage pulmonary disease. Advances in surgical techniques, the development of better immunosuppressive agents, and the standardization of care have improved patient survival and quality of life. This article includes statistics on men versus women diagnosed with Chronic Obstructive Pulmonary Disease. Included with this article is a case report of a 52-year-old white male who had undergone a bilateral lung transplant. The patient’s medication protocol is discussed within this article, including the use of inhaled cyclosporine to treat acute cellular rejection, one of the major complications associated with lung transplantation. The formulation for the cyclosporine for aerosol that was prepared by a compounding pharmacist is included with this article.

Related Keywords: Linda F. McElhiney, PharmD, RPh, FIACP, FASHP, inhaled cyclosporin, lung transplantation, pulmonary disorders, chronic obstructive pulmonary disease, COPD, immunosuppressive agent, immunosuppressant, case report, formulation, aerosolization, adverse effects, inhalation therapy, aerosol

Related Categories: FORMULATIONS, CASE REPORTS, ALLERGY/IMMUNOLOGY/INFLAMMATION, DOSAGE FORMS/DRUG CARRIERS, RESPIRATION/LUNG/BREATHING

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