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Abstract:  Skin conditions such as psoriasis and eczema negatively impact the patient’s quality of life; the primary goal of topical treatments is to minimize the disease-specific symptoms. This case report discusses the management of two refractory psoriasis skin lesions in an adult male using a topical compounded formula. The psoriasis symptoms were assessed quantitatively using two validated research instruments, the Psoriasis Symptom Inventory, and an adapted Numeric Rating Scale. A qualitative assessment was also performed by evaluating the digital photographs taken by the patient during the course of treatment. The compounded formula containing zinc pyrithione, clobetasol propionate, and cyanocobalamin in the Professional Compounding Centers of America’s proprietary base PCCA XemaTop, applied topically for three weeks, significantly reduced the patient’s self-reported psoriasis symptoms and improved his overall condition by 81.2%. This successful case report is important evidence for healthcare professionals when considering new, innovative topical compounded formulas for managing skin conditions such as psoriasis and eczema.

Related Keywords: inflammatory skin disorders, psoriasis, eczema, autoimmune disease, dermatitis, dry skin, boswellic acid, avenanthramides, phosphatidylglycerol, ceramide, lamellar bilayers, case report, topical preparation, zinc pyrithione, topical corticosteroid, clobetasol proprionate micronized, cyanocobalamin, formulation, nitric oxide blocker, inflammation, anti-inflammatory agent, cytostatic agent, antimicrobial agent, patient self assessment, Psoriasis Symptom Inventory, numeric rating scale, patient-reported outcome

Related Categories: DERMATOLOGY, EXCIPIENTS, FORMULATIONS, CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS, PATIENT ASSESSMENT

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