Abstract

Extemporaneous Preparation of Sertraline Cream for Transdermal Administration

Author(s): Wynn Tom, Goetsch Daniel

Issue: May/Jun 2011 - Volume 15, Number 3

Page(s): 200-203

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  • Extemporaneous Preparation of Sertraline Cream for Transdermal Administration Page 2
  • Extemporaneous Preparation of Sertraline Cream for Transdermal Administration Page 3
  • Extemporaneous Preparation of Sertraline Cream for Transdermal Administration Page 4

Abstract

The antidepressant effects of selective serotonin reuptake inhibitors are currently attributed to responses exhibited after periods of prolonged administration. Postulations have been formed accrediting the successful treatment of anxiety-related disorders with selective serotonin reuptake inhibitors to a similar mechanism of action as displayed in the treatment of depression. One of the drugs in this class is sertraline. This article provides a case report of a pediatric patient diagnosed with an anxiety disorder who was treated with transdermal sertraline. The compounding of dosage forms tailored to meet patient-specific needs may be an integral part in the successful delivery of selective serotonin reuptake inhibitor therapy.

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