Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy

Author(s): Griffee Chris, Delano Amy

Issue: Mar/Apr 2012 - Volume 16, Number 2
View All Articles in Issue

Page(s): 110-114

Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy Page 1

Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy Page 2

Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy Page 3

Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy Page 4

Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy Page 5

Download in electronic PDF format for $65

Abstract: A 61-year-old postmenopausal Caucasian woman presented to the pharmacy to re-initiate hormone therapy after having discontinued treatment for three years. She had discontinued previous hormone therapy due to severe hyperpigmentation of both nipples and areola. She stated that her nipples and areola had turned black, as if they had been burned. This reaction seemed unique, and we felt that it warranted further investigation.

Related Keywords: Chris Griffee, Amy Delano, PharmD, case report, hormone replacement therapy, adverse affects, hyperpigmentation, skin darkening, nipples, areola, topical preparation, transdermal administration, estradiol, estriol, progesterone, lozenge, formulations

Related Categories: DERMATOLOGY, FORMULATIONS, HRT, CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS

Printer-Friendly Version

Title/Author (Click for Abstract / Details / Purchase)	Issue/Page View/Buy
Related Articles from IJPC
Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy Griffee Chris, Delano Amy	Mar/Apr 2012 Pg. 110-114
Veterinary Transdermal Medications: A to Z Davidson Gigi S	Mar/Apr 2003 Pg. 106-113
The Science Behind Hormone Replacement Therapy, Part 1 Wepfer Scott T	Nov/Dec 2001 Pg. 462-464
Bioidentical Hormone Replacement Therapy, Part 3, A Review of Wepfer Scott T	Mar/Apr 2002 Pg. 142-146
Novel Approaches to Topical Psoriasis Therapy Koyama Gregory, Liu Jenny, Scaffidi Alyse, Khazraee Maryam, Epstein Benjamin	Sep/Oct 2015 Pg. 357-365
Natural Progesterone in Natural Hormone Replacement Therapy, The Role of Girouard Lorinda G, Holm Richard C	May/Jun 2001 Pg. 218-220
Efficacy and Clinical Value of Commonly Compounded Hormone Replacement Therapy: A Literature Review Beshay Sarah M, Rivera Gerard, Balthasar Jan, Florea Naomi	Jan/Feb 2015 Pg. 6-12
Using Serum Hormone Analysis to Develop Hormone Replacement Therapy Regimens - Part 2 Ford Gina, Garcia Lea	Jan/Feb 2001 Pg. 52-54
In Vitro Skin Penetration and Skin Content of Progesterone from Various Topical Formulations Heustess Allie, Asbill Scott, Eagerton David, Arnold John	Nov/Dec 2014 Pg. 512-515
Case Reports: Long-Term Effects of Topical Progesterone Cream Application; Progesterone Suppositories for PMS Ilyia Elias F, McLure Deborah, Farhat Michel Y	Sep/Oct 1999 Pg. 352-354