Abstract
Bilateral Areolar Hyperpigmentation Following Transdermal Administration of Compounded Hormone Replacement Therapy
Author(s): Griffee Chris, Delano Amy
Issue: Mar/Apr 2012 - Volume 16, Number 2
Page(s): 110-114
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Abstract
A 61-year-old postmenopausal Caucasian woman presented to the pharmacy to re-initiate hormone therapy after having discontinued treatment for three years. She had discontinued previous hormone therapy due to severe hyperpigmentation of both nipples and areola. She stated that her nipples and areola had turned black, as if they had been burned. This reaction seemed unique, and we felt that it warranted further investigation.
Related Keywords
- case report
- hormone replacement therapy
- adverse affects
- hyperpigmentation
- skin darkening
- nipples
- areola
- topical preparation
- transdermal administration
- estradiol
- estriol
- progesterone
- lozenge
- formulations
Related Categories
- DERMATOLOGY
- FORMULATIONS
- HRT
- CASE REPORTS
- DOSAGE FORMS/DRUG CARRIERS
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