International Journal of Pharmaceutical Compounding

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Oral Mucosal Immunotherapy Using a Toothpaste Delivery System for the Treatment of Allergic Rhinitis

Author(s): Reisacher William, Rudner Shara, Kotik Viktoriya

Issue: Jul/Aug 2014 - Volume 18, Number 4
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Page(s): 287-290

Oral Mucosal Immunotherapy Using a Toothpaste Delivery System for the Treatment of Allergic Rhinitis Page 1

Oral Mucosal Immunotherapy Using a Toothpaste Delivery System for the Treatment of Allergic Rhinitis Page 2

Oral Mucosal Immunotherapy Using a Toothpaste Delivery System for the Treatment of Allergic Rhinitis Page 3

Oral Mucosal Immunotherapy Using a Toothpaste Delivery System for the Treatment of Allergic Rhinitis Page 4

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Abstract: Oral mucosal immunotherapy is a novel method of delivering allergenic extracts to the tolerogenic oropharyngeal mucosa using a compounded toothpaste vehicle. This article describes three cases where individuals with seasonal allergic rhinitis demonstrated symptom improvement as well as decreased skin reactivity after using oral mucosal immunotherapy in a pre-seasonal and co-seasonal fashion.

Related Keywords: allergic rhinitis, sublingual immunotherapy, patient compliance, patient adherence, oral mucosa, mucosal administration, glycerin-based toothpaste delivery vehicle, case reports, allergy outcome survey, skin-prick testing, oral mucosal immunotherapy, toothbrushing

Related Categories: EAR NOSE THROAT, EXCIPIENTS, CASE REPORTS, ALLERGY/IMMUNOLOGY/INFLAMMATION, PATIENT COMPLIANCE, DOSAGE FORMS/DRUG CARRIERS

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