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Personalized Medicine and Customized Drug Delivery Systems: The New Trend of Drug Delivery and Disease Management

Author(s):  Soni Abhishek, Gowthamarajan Kuppusamy, Radhakrishnan Arun

Issue:  Mar/Apr 2018 - Volume 22, Number 2
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Page(s):  108-121

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Abstract:  Over the past few decades, the concept of personalized medicine has proved to play an important role in the healthcare sector. Personalized medicine modifies the current dosage forms according to the needs of the patient. Based on this improved concept, we are now able to bring out best treatment options for a particular individual leading to better therapeutic outcomes and decreased adverse effects. It also has the potential to identify the disease at an earlier stage. It links the diseased condition of a person to the basic genetic and molecular profile causing better understanding of the condition of the patient and to pick out better treatment options. This review is to enlighten the past, present, and future perspective of personalized medicine and how the personalized-medicine approach is used as customized drug delivery, as well as the regulatory aspects towards it. Personalized medicine has the potential to modify the way we recognize and manage our health problems and has already proven to have a huge impact on patient care and on clinical research. The impact of personalized medicine is expected to increase with an increased knowledge about the term and related technologies.

Related Keywords: drug delivery technologies, genomic analysis, molecular data, precision medicine, pharmacogenetics, pharmacogenomic testing, targeted pharmaceuticals, nanotechnology, nanomedicine, biomarkers, biochips, microarrays, proteomics, metabolome, customized dosage forms, orally disintegrating films, U.S. Food and Drug Administration, FDA

Related Categories: HISTORY, LEGAL, TECHNOLOGY, DOSAGE FORMS/DRUG CARRIERS, PATIENT ASSESSMENT, PROFESSIONAL ISSUES

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