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Abstract:  An important skin aging mechanism is oxidative stress. Reactive oxygen species in excess leads to skin integrity loss and visible changes. Antioxidants are able to prevent reactive oxygen species damage, making their supplementation important to slow down the aging process. We evaluated Vitis vinifera L. extract antioxidant potential to be applied for cosmetic purpose. The sample’s thin-layer chromatography profile and antioxidant results indicated a good antioxidant activity. The extract was incorporated into different formulations, and a stability study was conducted with the emulsion chosen. Organoleptic and physicochemical parameters were evaluated, as well as the microbial count. The formulation was found to be in compliance with current standards and has the potential to be further studied and used as an anti-aging cosmetic.

Related Keywords: Jacqueline Carneiro, PhD, Melissa Marques Gonçalves, MSc, Airton Vicente Pereira, PhD, skin aging, skin damage, oxidative stress, reactive oxygen species, skin integrity, antioxidants, Vitis vinifera L., skin care, anti-aging formulation, topical preparations, grape extract, phenolic compounds, emollients, formulation, cosmetic, stability

Related Categories: DERMATOLOGY, EXCIPIENTS, STABILITIES, COMPATIBILITIES, DOSAGE FORMS/DRUG CARRIERS

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