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A Compendium of Compounding Agents and Formulations, Part 2: Metronidazole, Misoprostol, and Phenytoin

Author(s):  Riepl Mike

Issue:  Mar/Apr 2022 - Volume 26, Number 2
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Abstract:  When compounded with synergistic ingredients, many pathogenicidal or anti-inflammatory drugs are particularly effective in resolving dermal or mucosal wounds that have proven refractory to treatment with standardized medications. In a customized preparation, such agents offer therapy that can be easily revised to repair injured tissues, minimize discomfort, and reduce morbidity. In this article, profiles of metronidazole, misoprostol, and phenytoin (drugs with often underappreciated wound-healing effects) are presented, and formulations designed to restore tissue integrity are provided for easy reference.

Related Keywords: Mike Riepl, RPh, wound healing, skin lesions, mucosal lesions, metronidazole, misoprostol, phenytoin, formulations, tissue integrity, topical preparations, epithelialization, wound odors, collagen, peptic ulcers, diabetes, fibroblast proliferation, foot ulcers, decubitus ulcers, venous stasis ulcers, pressure ulcers, bedsores

Related Categories: DERMATOLOGY, FORMULATIONS, WOUND CARE, ALLERGY/IMMUNOLOGY/INFLAMMATION, DOSAGE FORMS/DRUG CARRIERS

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