Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide

Author(s):  Riepl Mike

Issue:  May/Jun 2022 - Volume 26, Number 3
View All Articles in Issue

Page(s):  189-193

A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide Page 1
A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide Page 2
A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide Page 3
A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide Page 4
A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide Page 5

Download in electronic PDF format for $65

Abstract:  Since antiquity, the safety and effectiveness of topical and transdermal medications in treating a host of somatic conditions, including disorders that afflict the skin, have been appreciated. Those drug-delivery forms offer convenient self-administration; obviate gastrointestinal-tract absorption and hepatic–first-pass metabolism, thereby improving bioavailability and maintaining sufficient drug concentration within the therapeutic window; and facilitate the transmission of the largest fraction of drug molecules to the target area, thus maximizing therapeutic potential and reducing systemic drug toxicity. In this article, gentamicin and benzoyl peroxide, neither of which is commercially available currently in an easily modifiable topical or transdermal form, are profiled, and 2 compounded formulations are provided for easy reference.

Related Keywords: Mike Riepl, RPh, gentamicin, benzoyl peroxide, transdermal administration, topical preparations, formulations, skin disorders, wound healing, cutaneous infections, pressure ulcers, oral lesions, mouth ulcers, burns

Related Categories: DERMATOLOGY, FORMULATIONS, WOUND CARE, DOSAGE FORMS/DRUG CARRIERS, INFECTIOUS DISEASE

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
A Compendium of Compounding Agents and Formulations, Part 3: Gentamicin Sulfate and Benzoyl Peroxide
Riepl Mike
May/Jun 2022
Pg. 189-193

Current Topical Treatments in Wound Healing - Part 1
Helmke Christopher D
Jul/Aug 2004
Pg. 269-274

Veterinary Transdermal Medications: A to Z
Davidson Gigi S
Mar/Apr 2003
Pg. 106-113

Options in Wound Care
Kincaid Michele R
Mar/Apr 2002
Pg. 92-95

A Compendium of Compounding Agents and Formulations, Part 6: Additional Preparations for Refractory Dermal-wound Healing
Riepl Mike
Nov/Dec 2022
Pg. 480-488

Compounding Pearls -- Wound Care: Burn Healing, Part 2
Riepl Mike
Jul/Aug 2020
Pg. 282-285

Compounding Pearls -- Wound Care: Diabetic Foot Ulcers, Part 1
Riepl Mike
May/Jun 2020
Pg. 182-186

A Compendium of Compounding Agents and Formulations, Part 2: Metronidazole, Misoprostol, and Phenytoin
Riepl Mike
Mar/Apr 2022
Pg. 94-98

Compounding Pearls -- Wound Care: Burn Healing, Part 1
Riepl Mike
May/Jun 2020
Pg. 188-193

A Compendium of Compounding Agents and Formulations, Part 5: Timolol and Beta-glucans
Riepl Mike
Sep/Oct 2022
Pg. 364-368

Particle Measuring Systems - USP <797> Environmental Monitoring Solutions