Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Compounding Pearls -- Wound Care: Diabetic Foot Ulcers, Part 2

Author(s):  Riepl Mike

Issue:  Jul/Aug 2020 - Volume 24, Number 4
View All Articles in Issue

Abstract:  Persistent diabetic foot ulcers can be difficult to treat. Success in doing so is based on understanding the differences between chronic- and acute-wound healing in general, the unique characteristics of those painful ulcers, and methods of treating them with pharmacotherapy that is safe and effective, especially in patients with multiple health┬áchallenges. When conventional treatments that rely on standard drug combinations, doses, and dosage forms do not promote healing in such cases, a pharmaceutical compound that can be customized in those respects may do so. In this article, which is the second in a 2-part series, those issues are addressed and formulations shown to be effective in resolving chronic wounds are provided. To my knowledge, at the time of this writing, the drugs in those compounds are not available, either alone or in combination, in any commercially available product designed for topical application to a healing wound.

Related Keywords: Mike Riepl, RPh, diabetic foot ulcers, diabetes, wound care, wound healing, chronic wounds, reepithelialization, acute wounds, formulations, drug combinations, phenytoin, misoprostol, insulin, naltrexone, nonhealing wounds, topical preparations, extracellular matrix, collagen, granulation, prostaglandin receptor EP2, dendritic cells, inflammation, proinflammatory cytokines, keratinocyte migration, liothyronine sodium, simvastatin


Printer-Friendly Version

Download in electronic PDF format for $45

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Options in Wound Care Kincaid Michele R Mar/Apr 2002 92-95 Buy
Current Topical Treatments in Wound Healing - Part 1 Helmke Christopher D Jul/Aug 2004 269-274 Buy
Compounding Pearls -- Wound Care: Diabetic Foot Ulcers, Part 2 Riepl Mike Jul/Aug 2020 278-281 Buy
Compounding Pearls -- Wound Care: Diabetic Foot Ulcers, Part 1 Riepl Mike May/Jun 2020 182-186 Buy
Case Report: Wound Care of a Diabetic Foot Ulcer Wynn Tom Jul/Aug 2004 265-267 Buy
Five Compounds for Treating Diabetes-Related Conditions Meece Jerry May/Jun 2003 170-174 Buy
Compounding Pearls -- Wound Care: Base Selection Riepl Mike Mar/Apr 2020 98-102 Buy
Compounding Pearls -- Wound Care: Burn Healing, Part 1 Riepl Mike May/Jun 2020 188-193 Buy
Case Report: Diabetic Foot Ulcer Infection Treated with Topical Compounded Medications Agbi Kelechi E, Carvalho Maria, Phan Ha, Tuma Cristiane Jan/Feb 2017 22-27 Buy
Compounding Pearls -- Wound Care: Burn Healing, Part 2 Riepl Mike Jul/Aug 2020 282-285 Buy