Abstract

Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy

Author(s): Karara Adel H, Hines Ryan, Demir Zehra, Nnorom Bethran, Horsey Robert, Twigg Geoffrey

Issue: Nov/Dec 2016 - Volume 20, Number 6

Page(s): 461-467

Download in electronic PDF format for $75
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 1
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 2
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 3
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 4
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 5
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 6
  • Evaluation of the Most Frequently Prescribed Extemporaneously Compounded Veterinary Medications at a Large Independent Community Pharmacy Page 7

Abstract

Extemporaneous drug formulation is essential to provide optimal pharmaceutical care to veterinary patients. The need for this is exacerbated by the fact that commercially produced veterinary-specific products, without a human indication, require specialty veterinary manufacturing facilities and a new animal drug application process to gain marketing approval. This study examined the prescription patterns of extemporaneously compounded veterinary preparations in the compounding department at a large independent community pharmacy. Data was obtained from a total of 1348 prescriptions requiring extemporaneous compounding over the course of a two-year period (2014–2015). A database was constructed and each compounded prescription was allocated to a therapeutic category based on the American Hospital Formulary Service Drug Information. Data analysis showed that the most commonly prescribed preparations belonged to the central nervous system (39%), anti-infective agents (21%), and hormones (12%) therapeutic categories. Overall, suspensions were the most dispensed (47%), extemporaneously compounded dosage forms followed by solutions (28%), and capsules (10%). The majority (88%) of compounded preparations were administered by the oral route. The top three drugs that are compounded for veterinary medicine were (1) potassium bromide oral solution for canine epilepsy, (2) methimazole solution used to treat hyperthyroidism in cats, and (3) metronidazole suspension, an antibiotic for the treatment of diarrhea and other infections in dogs and cats. Remarkably, our findings are in good agreement with previously published survey data on the top drugs that are compounded for veterinary medicine. In the era of personalized medicine, veterinary extemporaneous compounding for specialized needs will continue to play an important role providing optimum therapy for veterinary patients.

Related Keywords

Related Categories

Printer-Friendly Version

Related Articles from IJPC

Issue/Page
View/Buy
Title/Author
(Click for Abstract / Details / Purchase)
Mar/Apr 2003
Pg. 106-113
Author(s): Davidson Gigi S
Nov/Dec 2016
Pg. 461-467
Nov/Dec 2014
Pg. 462-468
May/Jun 2004
Pg. 181-185
Jan/Feb 2014
Pg. 6-12
Sep/Oct 2019
Pg. 422-427
Sep/Oct 2019
Pg. 428-433
Jan/Feb 2017
Pg. 47-56
Author(s): Akers Michael J
Jul/Aug 2001
Pg. 282-283
Author(s): Davidson Gigi S
Jan/Feb 2018
Pg. 19-24
Sep/Oct 2016
Pg. 367-374
Jan/Feb 2009
Pg. 14-18
Jul/Aug 2001
Pg. 310-312
Author(s): Allen Loyd V Jr
Mar/Apr 2001
Pg. 86-88
Author(s): Simpson Barbara S
Mar/Apr 2014
Pg. 159-161
Nov/Dec 2015
Pg. 491-500
Author(s): Akers Michael J
Mar/Apr 2016
Pg. 114-122
Jan/Feb 2017
Pg. 19-21
Jul/Aug 2004
Pg. 277-283
Author(s): Davidson Gigi S
Sep/Oct 2007
Pg. 357-362
Author(s): DeVeau Ian