Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Preventing Leakage in Oil-Filled Capsules

Author(s):  Allen Loyd V Jr

Issue:  Sep/Oct 1999 - Natural Hormone Replacement Therapy
View All Articles in Issue

Abstract:  A significant percentage of the practice of NuCara Pharmacy in Waterloo, IA, involves veterinary compounding; and one oft he pharmacy’s most popular veterinary compounds is a diethylstilbestrol capsule used for estrogen-responsive incontinence in spayed female dogs. In the past, the pharmacy used vegetable oil as a component in the formulation of these capsules, with no problems. However, last April personnel began noticing leakage problems with some oil-filled capsules. To overcome this problem, an innovative technique was developed by Anthony H. Lake, MT (ASCP), chemist in the compounding laboratory. The technique is described here.

Related Keywords: DES, diethylstilbestrol, incontinence, oil-filled capsules, partially hydrogenated cottonseed oil, vegetable oil, veterinary compounding

Related Categories: SUPPORT

Printer-Friendly Version

Download in electronic PDF format for $65

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Preventing Leakage in Oil-Filled Capsules Allen Loyd V Jr Sep/Oct 1999 364 Buy
Veterinary Transdermal Medications: A to Z Davidson Gigi S Mar/Apr 2003 106-113 Buy
Dry Heat Sterilization of Parenteral Oil Vehicles Kupiec Thomas C, Matthews Parrish, Ahmad Riaz May/Jun 2000 223-224 Buy
Oleaginous Vehicles, Featured Excipient: Allen Loyd V Jr Nov/Dec 2000 470-472 Buy
Effect of Emulsifier Pairs on Physical Stability of Emulsions Containing Three Different Natural Oils Boonme Prapaporn, Maneenuan Duangkhae Nov/Dec 2014 516-519 Buy
Accuracy Considerations in Sterile Compounding Akers Michael J Mar/Apr 2017 133-142 Buy
Compounding with Pracaxi Versus Copaiba Oil Magutu Tom Jul/Aug 2022 277-281 Buy
Compounding in the Pharmacy Curriculum: Beyond the Basics Hinkle Amanda R, Newton Gail D May/Jun 2004 181-185 Buy
Premixed Oil Phase for Preparing Oil-in-Water (O/W) Emulsions Allen Loyd V Jr Nov/Dec 2003 463 Buy
Estradiol Valerate 40-mg/mL in Oil Injection Allen Loyd V Jr Nov/Dec 2015 509 Buy
Particle Measuring Systems - USP <797> Environmental Monitoring Solutions