Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

Preventing Leakage in Oil-Filled Capsules

Author(s):  Allen Loyd V Jr

Issue:  Sep/Oct 1999 - Natural Hormone Replacement Therapy
View All Articles in Issue

Page(s):  364

Preventing Leakage in Oil-Filled Capsules Page 1

Download in electronic PDF format for $75

Abstract:  A significant percentage of the practice of NuCara Pharmacy in Waterloo, IA, involves veterinary compounding; and one oft he pharmacy’s most popular veterinary compounds is a diethylstilbestrol capsule used for estrogen-responsive incontinence in spayed female dogs. In the past, the pharmacy used vegetable oil as a component in the formulation of these capsules, with no problems. However, last April personnel began noticing leakage problems with some oil-filled capsules. To overcome this problem, an innovative technique was developed by Anthony H. Lake, MT (ASCP), chemist in the compounding laboratory. The technique is described here.

Related Keywords: DES, diethylstilbestrol, incontinence, oil-filled capsules, partially hydrogenated cottonseed oil, vegetable oil, veterinary compounding

Related Categories: SUPPORT

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Preventing Leakage in Oil-Filled Capsules
Allen Loyd V Jr
Sep/Oct 1999
Pg. 364

Accuracy Considerations in Sterile Compounding
Akers Michael J
Mar/Apr 2017
Pg. 133-142

Dry Heat Sterilization of Parenteral Oil Vehicles
Kupiec Thomas C
, Matthews Parrish, Ahmad Riaz
May/Jun 2000
Pg. 223-224

Veterinary Transdermal Medications: A to Z
Davidson Gigi S
Mar/Apr 2003
Pg. 106-113

Oleaginous Vehicles, Featured Excipient:
Allen Loyd V Jr
Nov/Dec 2000
Pg. 470-472

Effect of Emulsifier Pairs on Physical Stability of Emulsions Containing Three Different Natural Oils
Boonme Prapaporn
, Maneenuan Duangkhae
Nov/Dec 2014
Pg. 516-519

The Basics of Compounding: Compounding Powder-Filled Capsules
Allen Loyd V Jr
May/Jun 1999
Pg. 209-215

Compounding with Pracaxi Versus Copaiba Oil
Magutu Tom
Jul/Aug 2022
Pg. 277-281

Premixed Oil Phase for Preparing Oil-in-Water (O/W) Emulsions
Allen Loyd V Jr
Nov/Dec 2003
Pg. 463

Basics of Compounding: Special Capsules
Allen Loyd V Jr
May/Jun 2016
Pg. 209-214

Technology Spotlight: Capsule-Filling Machines
Allen Loyd V Jr
Jan/Feb 2002
Pg. 31

Progesterone-Estradiol-Testosterone in Oil Capsules
Allen Loyd V Jr
Jan/Feb 1998
Pg. 54

Progesterone in Oil Capsules
Allen Loyd V Jr
Jan/Feb 1998
Pg. 55

Testosterone 25-mg in Oil Capsules
Allen Loyd V Jr
Jul/Aug 2002
Pg. 301

Progesterone 100-mg in Peanut-Oil Capsules
Allen Loyd V Jr
May/Jun 1997
Pg. 182

Triple Estrogen 2.5-mg in Oil Capsules
Allen Loyd V Jr
May/Jun 1997
Pg. 185

Coenzyme Q10 100-mg-in-Oil Capsules
Glasnapp Andrew
Jul/Aug 2003
Pg. 291

Estradiol Valerate 40-mg/mL in Oil Injection
Allen Loyd V Jr
Nov/Dec 2015
Pg. 509

Antimicrobial Activity of Copaiba (Copaifera officinalis) and Pracaxi (Pentaclethra macroloba) Oils against Staphylococcus aureus: Importance in Compounding for Wound Care
Guimarães Anna Luísa Aguiar
, Cunha Elisa Alves, Matias Fernanda Oliveira, Garcia Patrícia Guedes, Danopoulos Panagiota, Swikidisa Rosita, Pinheiro Vanessa Alves, Nogueira Rodrigo José Lupatini
Jan/Feb 2016
Pg. 58-62

Ursodiol 100 mg/mL in Cod Liver Oil, Veterinary
Allen Loyd V Jr
May/Jun 2020
Pg. 232

Return to Top