Bot Detector
Download FREE Sample Issue or Article
Subscribe Today
A subscription to IJPC includes a print copy delivered by postal mail and on-line access to electronic PDF copies of your subscribed issues.

Effect of Emulsifier Pairs on Physical Stability of Emulsions Containing Three Different Natural Oils

Author(s):  Boonme Prapaporn, Maneenuan Duangkhae

Issue:  Nov/Dec 2014 - Volume 18, Number 6
View All Articles in Issue

Abstract:  The purpose of this study was to formulate oil-in-water (o/w) emulsions containing 40% w/w natural oil (i.e., olive oil, rice bran oil, or sesame oil), 10% w/w emulsifier blend, and 50% w/w water. The hydrophile-lipophile balance system was used to calculate the amount of each non-ionic emulsifier in the formulations. All studied oils have an identical required hydrophile-lipophile balance of 7. In emulsifier blend, polyoxyethylene (20) sorbitan monooleate (hydrophile-lipophile balance = 15.0) was fixed as a high hydrophile-lipophile balance emulsifier, while sorbitan monostearate (hydrophile-lipophile balance = 4.7) or sorbitan monooleate (hydrophile-lipophile balance = 4.3) was used as a low hydrophile-lipophile balance emulsifier. The effect of emulsifier pairs on physical properties of the prepared samples was investigated. The physical stability of the emulsions was evaluated at ambient temperature (˜30°C) after storage for 30 and 60 days. It was found that emulsifier pairs influenced both characteristics and stability of the samples. Sorbitan monostearate could provide stable emulsions of all studied natural oils when blended with polyoxyethylene (20) sorbitan monooleate while sorbitan monooleate could not. From the obtained results, it could be concluded that not only suitable hydrophile-lipophile balance but also suitable emulsifier pair were important parameters in emulsion formulations.

Related Keywords: Prapaporn Boonme, PhD, Duangkhae Maneenuan, BSc, oil-in-water emulsions, natural oils, emulsifier blends, olive oil, rice bran oil, sesame oil, emollients, moisturizers, skin care, stable emulsions, physical stability, hydrophile-lipophile balance


Printer-Friendly Version

Download in electronic PDF format for $55

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Effect of Emulsifier Pairs on Physical Stability of Emulsions Containing Three Different Natural Oils Boonme Prapaporn, Maneenuan Duangkhae Nov/Dec 2014 516-519 Buy
Physical Stability of Coconut Oil Lotions Formulated Using a Hydrophile-lipophile System of Various Emulsifier Pairs Boonme Prapaporn, Maneenuan Duangkhae, Channarong Sunee Jul/Aug 2013 347-350 Buy
Dry Heat Sterilization of Parenteral Oil Vehicles Kupiec Thomas C, Matthews Parrish, Ahmad Riaz May/Jun 2000 223-224 Buy
Oleaginous Vehicles, Featured Excipient: Allen Loyd V Jr Nov/Dec 2000 470-472 Buy
Rice Bran Oil: Preparation and Evaluation of Novel Liquisolid and Semisolid Formulations Ammar Hussein O, Al-Okbi Sahar Y, Mostafa Dina M, Helal Amr M Nov/Dec 2012 516-523 Buy
Premixed Oil Phase for Preparing Oil-in-Water (O/W) Emulsions Allen Loyd V Jr Nov/Dec 2003 463 Buy
Acacia and Mineral Oil Emulsion NF Al-Achi Antoine, Mosley Anita, Patlolla Swapna Jan/Feb 2006 44 Buy
Experimenting with a New Emulsifying Agent (Tahini) in Mineral Oil Emulsion Al-Achi Antoine, Greenwood Robert, Akin-Isijola Austin Jul/Aug 2000 315-317 Buy
Preventing Leakage in Oil-Filled Capsules Allen Loyd V Jr Sep/Oct 1999 364 Buy
The Basics of Compounding Emulsions, Part 2 Allen Loyd V Jr May/Jun 2001 198-201 Buy