Abstract

Update on Managing Neuropathic Pain

Author(s): McNulty Jack P, Muller George

Issue: May/Jun 2009 - Pain Management

Page(s): 182-190

Download in electronic PDF format for $75

Abstract

Severe chronic neuropathic pain, which can profoundly and negatively affect quality of life, is usually caused by damage to peripheral nerve tissue from various physical, thermal, or chemical agents and is diffi cult to relieve. Commonly used opioids are quite effective in relieving nociceptive pain, but nerves that are damaged send pain-sensing fibers into an area of the spinal cord in which there are no mu or kappa receptors to receive opioids or the endogenous endorphins that relieve pain. Clinicians who treat neuropathic pain face daunting therapeutic challenges, but specifi c analgesic agents have proven effective in relieving that excruciating discomfort. In this article, drugs that target neuropathic pain are discussed, and case reports of patients who have overcome nerve-related pain are presented. Formulations for effective analgesic preparations useful in treating neuropathic pain are included.

Related Keywords

Related Categories

Printer-Friendly Version

Related Articles from IJPC

Issue/Page View/Buy	Title/Author (Click for Abstract / Details / Purchase)
May/Jun 2010 Pg. 200-203	Topical Medications for Orofacial Neuropathic Pain Author(s): Bramwell Bethany L
May/Jun 2010 Pg. 182-192	Compounded Analgesic Therapy for Disorders of Movement: Arthritis, Neuropathic Pain, and Postpolio Syndrome Author(s): Brown Scott, Erickson Brian, Muller George, Bryant-Snure Susan J, Mestayer Richard F III
May/Jun 2009 Pg. 182-190	Update on Managing Neuropathic Pain Author(s): McNulty Jack P, Muller George
Jan/Feb 2022 Pg. 65-71	Physical Stability and Release Profile of Compounded Gabapentin Containing Pluronic Lecithin Organogel for Neuropathic Pain Management Author(s): Hong Eun Ji, Sumanasekera Wasana, Le Uyen Minh
Mar/Apr 2016 Pg. 107-113	Topical Ketamine: A Review of the History, Mechanisms, Uses, Safety, and Future Author(s): Rabi Joseph
May/Jun 2008 Pg. 182-190	Topical Treatment of Neuropathic Pain Author(s): Vadaurri Vince
Jan/Feb 2002 Pg. 4-6	Clinical Nuggets and Pearls: Chronic Neuropathic Pain and Opioid Tolerance Author(s): Jones Marty
Nov/Dec 2016 Pg. 517-520	Topical Ketamine 10% for Neuropathic Pain in Spinal Cord Injury Patients: An Open-Label Trial Author(s): Rabi Joseph, Minori Joshua, Abad Hasan, Lee Ray, Gittler Michelle
May/Jun 2010 Pg. 204-206	Managing Pain with Transdermal Ketoprofen Author(s): Williams KaCee D
Jul/Aug 2014 Pg. 278-286	Compounded Pain Formulations: What is the Evidence? Author(s): Asbill Scott, Sweitzer Sarah M, Spigener Shuler, Romero-Sandoval Alfonso
Mar/Apr 2024 Pg. 100-109	Compounded Pain Formulations: What is the Evidence? Author(s): Asbill Scott, Sweitzer Sarah M, Spigener Shuler, Romero-Sandoval Alfonso
Nov/Dec 2019 Pg. 496-503	Compounded Topical Gabapentin for Neuropathic Pain: Does Choice of Base Affect Efficacy? Author(s): Shakshuki Ayah, Agu Remigius U
Mar/Apr 2024 Pg. 111-116	Efficacy and Clinical Value of Commonly Used Ingredients in Pain Management Compounds: A Literature Review Author(s): Beshay Sarah M, Rivera Gerard, Balthasar Jan, Florea Naomi
Jul/Aug 2015 Pg. 295-300	Efficacy and Clinical Value of Commonly Used Ingredients in Pain Management Compounds: A Literature Review Author(s): Beshay Sarah M, Rivera Gerard, Balthasar Jan, Florea Naomi
Nov/Dec 2010 Pg. 514	Baclofen 5%, Gabapentin 5%, Ketoprofen 10%, and Lidocaine 5% in Pluronic Lecithin Organogel Author(s): Allen Loyd V Jr
Jan/Feb 2000 Pg. 6-15	Chronic Neuropathic Pain: Pharmacological Interventions in New Millennium Author(s): Jones Marty
Jul/Aug 2000 Pg. 253-254	Ketamine for Pain in Hospice Patients Author(s): Wood Robert M
Mar/Apr 2006 Pg. 159-160	PostScription: Treatment of Chronic Pain with Methadone or Levorphanol Author(s): McNulty Jack P
Mar/Apr 2015 Pg. 167-173	Analgesic Efficacy and Transdermal Penetration of Topical Gabapentin Creams: Finding an Optimal Dose and Pre-treatment Time Author(s): Heustess Allie, Spigener Shuler, Sweitzer Sarah, Romero-Sandoval Alfonso, Asbill Scott
May/Jun 2014 Pg. 182-188	A Brief Survey on Prescriber Beliefs Regarding Compounded Topical Pain Medications Author(s): Warner Meredith, Tuder Dmitry