Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2

Author(s):  Gillson George R, Zava David T

Issue:  Sep/Oct 2003 - After the Women's Health Initiative Trial
View All Articles in Issue

Page(s):  330-338

A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 1
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 2
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 3
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 4
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 5
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 6
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 7
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 8
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2 Page 9

Download in electronic PDF format for $75

Abstract:  This second part of a two-part series focuses on a discussion of progesterone and progestins differentiating the two in terms of synergy between estradiol and progesterone, balance between estrone and estrogen sulfate within tumor cells, protection of the uterine linings and impact on cardiovascular function; and bioidentical progesterones (oral and topical). Sidebars provide examples of studies showing adverse effects of medroxyprogesterone acetate on cardiovascular health, progesterone‚Äôs beneficial effects on cardiovascular function, results with bioidentical progesterone, results with topical progesterone and a protocol for combined hormone replacement therapy using progesterone skin cream. The authors conclude that physicians should not turn their backs on patients suffering from hormonal deficiencies in the absence of large clinical trials with bioidentical hormones since the literature suggests estradiol and estriol would be good estrogens to use and transdermal delivery of hormones is advantageous over oral delivery. With oral delivery, doctors should rethink dosing and consider impact on other relevant parameters. It appears that certain progestins should be avoided in favor of bioidentical progesterone, and saliva testing can allow monitoring of hormone levels. With good follow-up, clinical judgment and laboratory backup, there is enough information about hormone replacement to offer bioidentical hormone replacement therapy as a viable option. A patient handout on hormone replacement therapy accompanies the article.

Related Keywords: Bioidentical hormone replacement therapy, for women, Estradiol, for women, Estrogen sulfate, for women, Estrone, for women, Hormone replacement therapy, for women, Medroxyprogesterone acetate, and cardiovascular health, Medroxyprogesterone acetate, for women, Progesterone, bioidentical, for women, Progesterone, and cardiovascular function, Progestins, for women

Related Categories: HRT

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 2
Gillson George R
, Zava David T
Sep/Oct 2003
Pg. 330-338

Androgen Deficiency in Women: Understanding the Science, Controversy and Art of Treating Our Patients - Part 1
Cutter Christopher B
Jan/Feb 2004
Pg. 16-21

A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 1
Gillson George R
, Zava David T
Jul/Aug 2003
Pg. 250-256

Women's Oral Health: Is There a Hormonal Link?
Preckshot John
Jan/Feb 2004
Pg. 10-14

Androgen Deficiency in Women: Understanding the Science, Controversy and Art of Treating Our Patients - Part 2
Cutter Christopher B
Mar/Apr 2004
Pg. 96-99

The Science Behind Hormone Replacement Therapy, Part 1
Wepfer Scott T
Nov/Dec 2001
Pg. 462-464

Menopausal Symptom Relief and Side Effects Experienced by Women Using Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 1
Deleruyelle Laura J
Sep/Oct 2016
Pg. 359-364

Menopausal Symptom Relief and Side Effects Experienced by Women Using Compounded Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 2
Deleruyelle Laura J
Nov/Dec 2016
Pg. 447-454

The Effects of Compounded Bioidentical Transdermal Hormone Therapy on Hemostatic, Inflammatory, and Immune Factors; Cardiovascular Biomarkers; Quality of Life Measures; and Health Outcomes in Perimenopausal and Postmenopausal Women
Stephenson Kenna
, Neuenschwander Pierre F, Kurdowska Anna K
Jan/Feb 2013
Pg. 74-85

View Sample
Menopausal Women's Access Path to Bioidentical Hormone Replacement Therapy: An Exploratory Study
Moro Doris
, Young Wendy, Stein Richard, Isaac Winston, Goodman Deborah
Mar/Apr 2010
Pg. 165-170

Bioidentical Hormone Replacement Therapy, Part 3, A Review of
Wepfer Scott T
Mar/Apr 2002
Pg. 142-146

Menopausal Symptom Relief and Side Effects Experienced by Women Using Compounded Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 3
Deleruyelle Laura J
Jan/Feb 2017
Pg. 6-16

Using Serum Hormone Analysis to Develop Hormone Replacement Therapy Regimens - Part 2
Ford Gina
, Garcia Lea
Jan/Feb 2001
Pg. 52-54

Gender Bias in the Treatment of Menopausal Women: I am Hot as Hell and Not Going to Take It Anymore, Part 1
DeRosa Angela
Nov/Dec 2020
Pg. 466-470

Transdermal Progesterone: Effects on Menopausal Symptoms and on Thrombotic, Anticoagulant, and Inflammatory Factors in Postmenopausal Women
Stephenson Kenna
, Neuenschwander Pierre F, Kurdowska Anna K, Pinson Barbara, Price Carol
Jul/Aug 2008
Pg. 295-304

The Lived Experience of Perimenopausal and Menopausal Women Undergoing Treatment with Bioidentical Hormones
Holt-Waldo NaRisa Y
, Stephenson Kenna
Jul/Aug 2007
Pg. 292-296

Women's Health Book Reviews
Reed-Kane Dana
Sep/Oct 1999
Pg. 357-359

Book Reviews: Women's Health
Reed-Kane Dana
Nov/Dec 2000
Pg. 424-425

Hormone Replacement Therapy: Part 1 - The Evolution of Hormone Treatment
Lorentzen Jean
Sep/Oct 2001
Pg. 336-338

The Effectiveness of Sublingual and Topical Compounded Bioidentical Hormone Replacement Therapy in Post-menopausal Women: An Observational Cohort Study
Ruiz Andres D
, Daniels Kelly R
Jan/Feb 2014
Pg. 70-77

Return to Top