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Quality-Control Analytical Methods: Particulate Matter in Injections: What is It and What are the Concerns?

Author(s):  Tran Tuan, Kupiec Thomas C, Trissel Lawrence A

Issue:  May/Jun 2006 - Hormone Replacement Therapy
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Page(s):  202-204

Quality-Control Analytical Methods: Particulate Matter in Injections: What is It and What are the Concerns? Page 1
Quality-Control Analytical Methods: Particulate Matter in Injections: What is It and What are the Concerns? Page 2
Quality-Control Analytical Methods: Particulate Matter in Injections: What is It and What are the Concerns? Page 3

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Abstract:  The presence of particulate matter in intravenous injections, especially in large numbers, represents a potentially life-threatening health hazard. The United States Pharmacopeia has established procedures and standards to ensure the quality of intravenous injections, including particulate counts. Compounding pharmacists can reduce the incidence of adverse events in patients by assuring the quality of their preparations through filtration of intravenous preparations and analytical testing procedures.

Related Keywords: Tuan Tran, Thomas C. Kupiec, PhD, Lawrence A. Trissel, BS, RPh, FASHP, injection, quality control, particulates, United States Pharmacopeia, filtration, compounded sterile preparations, analytical testing methods

Related Categories: LEGAL, STERILE PREPARATIONS, QUALITY CONTROL, UNITED STATES PHARMACOPEIA CONVENTIONS, DOSAGE FORMS/DRUG CARRIERS

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