Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

Quality-Control Analytical Methods: Homogeneity of Dosing Forms

Author(s):  Kupiec Thomas C, Vu Nicole, Branscum David

Issue:  Jul/Aug 2008 - Hormone Replacement Therapy
View All Articles in Issue

Page(s):  340-343

Quality-Control Analytical Methods: Homogeneity of Dosing Forms Page 1
Quality-Control Analytical Methods: Homogeneity of Dosing Forms Page 2
Quality-Control Analytical Methods: Homogeneity of Dosing Forms Page 3
Quality-Control Analytical Methods: Homogeneity of Dosing Forms Page 4

Download in electronic PDF format for $75

Abstract:  Content uniformity is the degree of consistency in the amount of the drug substance among dosage units. There are two ways to determine content uniformity according to United States Pharmacopeial Chapter <905>; by means of Content Uniformity or Weight Variation methods. It is essential that compounding pharmacists know the different methods, how they work, and when to use each method to determine the content uniformity of their individual dosages.

Related Keywords: Thomas C. Kupiec, PhD, Nicole Vu, PhD, David Bransum, content uniformity, quality control, United States Pharmacopeia, USP Chapter <905>, quality assurance, standards, weight variation, dosage forms

Related Categories: QUALITY CONTROL, UNITED STATES PHARMACOPEIA CONVENTIONS, DOSAGE FORMS/DRUG CARRIERS

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Quality-Control Analytical Methods: Homogeneity of Dosing Forms
Kupiec Thomas C
, Vu Nicole, Branscum David
Jul/Aug 2008
Pg. 340-343

Quality-Control Analytical Methods: A Discussion of United States Pharmacopeia Chapter <71> Sterility Tests
Kupiec Thomas C
Sep/Oct 2007
Pg. 400-403

Quality-Control Analytical Methods: Glossary of Quality Control/Quality Assurance Terms in Pharmaceutical Compounding
Kupiec Thomas C
, Okeke Claudia, Allen Loyd V Jr, Denison Clay
Jul/Aug 2005
Pg. 300-302

Quality Control: Minor Chapters, Major Impacts: What United States Pharmacopeia Chapters <51>, <61>, <62>, and <1207> Mean for Your Compounding Practice
Kelley Brian
Mar/Apr 2021
Pg. 115-124

Quality-Control Analytical Methods: High-Performance Liquid Chromatography
Kupiec Thomas C
May/Jun 2004
Pg. 223-227

Quality-Control Analytical Methods: Gas Chromatography
Kupiec Thomas C
Jul/Aug 2004
Pg. 305-309

Quality Control Analytical Methods: Microbial Limit Tests for Nonsterile Pharmaceuticals, Part 1
Vu Nicole
, Lou Jessica R, Kupiec Thomas
May/Jun 2014
Pg. 213-221

Quality Control Analytical Methods: Method Validation
Klang Mark G
, Williams LaVonn A
Sep/Oct 2016
Pg. 381-386

Quality-Control Analytical Methods: Selecting an Analytical Method
Allen Loyd V Jr
Jan/Feb 2004
Pg. 61-64

Basics of Compounding: Implementing United States Pharmacopeia Chapter <1163> Quality Assurance in Pharmaceutical Compounding, Part 1
Allen Loyd V Jr
Mar/Apr 2012
Pg. 146-150

Quality Assurance and Quality Control, Part 1
Akers Michael J
Mar/Apr 2015
Pg. 121-124

Quality Assurance and Quality Control, Part 2
Akers Michael J
May/Jun 2015
Pg. 215-221

Quality-Control Analytical Methods: Specific-Gravity Determinations of Liquids and Semisolids
Allen Loyd V Jr
Nov/Dec 2003
Pg. 477-480

Quality Control Analytical Methods: A Guide to Quality Control Testing for the Compounding Pharmacist
Zolner William J
Jul/Aug 2006
Pg. 281-284

Applying Quality of Design Concepts to Pharmacy Compounding
Timko Robert J
Nov/Dec 2015
Pg. 453-463

Quality Assurance and Quality Control: Being Prepared for U.S. Food and Drug Administration Inspections and Staying in Compliance with United States Pharmacopeia Chapter <797>: Part 1
Martin Matt
Sep/Oct 2018
Pg. 401-404

Quality Control Analytical Methods: Physical Quantitative Verification of Nonsterile Compounded Preparations: Individualized Dosage Units
Sidhu Raman
Jul/Aug 2015
Pg. 307-310

Quality-Control Analytical Methods: Designing a Quality-Control Potency Testing Program for a Compounding Pharmacy
Zolner William J
Sep/Oct 2009
Pg. 412-418

Quality Control Analytical Methods: Strategies to Ensure a Robust Quality-control Microbiology Program
Griffiths Tricia
, Connors Anne
Mar/Apr 2013
Pg. 130-134

Quality-Control Analytical Methods: Osmolality and Osmometry
Allen Loyd V Jr
Mar/Apr 2004
Pg. 143-145

Return to Top