Abstract

Basics of Compounding with Dilutions and Concentrates

Author(s): Allen Loyd V Jr

Issue: Jan/Feb 2017 - Volume 21, Number 1

Page(s): 39-45

Download in electronic PDF format for $75
  • Basics of Compounding with Dilutions and Concentrates Page 1
  • Basics of Compounding with Dilutions and Concentrates Page 2
  • Basics of Compounding with Dilutions and Concentrates Page 3
  • Basics of Compounding with Dilutions and Concentrates Page 4
  • Basics of Compounding with Dilutions and Concentrates Page 5
  • Basics of Compounding with Dilutions and Concentrates Page 6
  • Basics of Compounding with Dilutions and Concentrates Page 7

Abstract

Pharmacists use various sources for obtaining the active pharmaceutical ingredient for compounding medications. In many cases, it is the pure drug (United States Pharmacopeia, National Formulary, or similar grade); in some cases, it can be a commercial dosage form; and, in some cases, it may be a dilution or concentrate. If the drug is not present at full strength, then adjustments may be necessary to obtain the required quantity of drug. Also, in many cases, it is necessary to use a dilution or a concentrate of a drug due to safety and quality reasons. Presented within this article are new sources of active pharmaceutical ingredients that are now available to aid pharmacists in meeting future United States Pharmacopeia <800> standards. It is critical that the pharmacist be aware of the strength of the drug and any other excipients that may be available.

Related Keywords

  • trituration
  • dilution
  • concentrates
  • stock preparations
  • liothyronine sodium
  • T3
  • levothyroxine sodium
  • T4
  • thyroid replacement
  • thyroid disorders
  • solid dilutions
  • stablity
  • liquid dilutions
  • aqueous concentrates
  • oil concentrates
  • sex hormones
  • sex steroids
  • estrogens
  • estrone
  • E1
  • estradiol
  • E2
  • estriol
  • E3
  • progesterone
  • P4
  • androgen
  • testosterone
  • menopause
  • hormone replacement therapy
  • HRT
  • hormone ratios
  • calculation aid

Related Categories

  • EXCIPIENTS
  • FORMULATIONS
  • HRT
  • SUPPORT
  • QUALITY CONTROL

Printer-Friendly Version

Related Articles from IJPC

Issue/Page
View/Buy		 Title/Author
(Click for Abstract / Details / Purchase)
Jan/Feb 2017
Pg. 39-45
Basics of Compounding with Dilutions and Concentrates
Author(s): Allen Loyd V Jr
Nov/Dec 2010
Pg. 508-510
Basics of Compounding: Basics of Compounding with Aliquots, Dilutions, and Concentrates
Author(s): Allen Loyd V Jr
Sep/Oct 2012
Pg. 376-380
Bioidentical Thyroid Replacement Therapy in Practice: Delivering a Physiologic T4-T3 Ratio for Improved Patient Outcomes with the Listecki-Snyder Protocol
Author(s): Snyder Scott, Listecki Robert E
Sep/Oct 2017
Pg. 418-425
Kinetic Analysis of Drug Release from Compounded Slow-release Capsules of Liothyronine Sodium (T3)
Author(s): Bakhteyar Hamid, Cassone Clayton, Kohan Hamed Gilzad, Sani Shabnam N
Nov/Dec 2008
Pg. 546
Liothyronine Sodium (T3) 5-mcg/0.1-mL Transdermal Cream
Author(s): Allen Loyd V Jr
Nov/Dec 2008
Pg. 545
Liothyronine Sodium (T3) 5-mcg/Hydrocortisone 5-mg Slow-Release Capsules
Author(s): Allen Loyd V Jr
Nov/Dec 2008
Pg. 547
Liothyronine Sodium (T3) 5-mcg/Selenium 100-mcg Slow-Release Capsules
Author(s): Allen Loyd V Jr
Nov/Dec 2008
Pg. 548
Liothyronine Sodium (T3) 5-mcg Slow-Release Capsules
Author(s): Allen Loyd V Jr
Jul/Aug 2010
Pg. 306-309
Thyroid Potency Calculations
Author(s): Stack Bob
Jul/Aug 2005
Pg. 268-273
Hypothyroidism: Optimizing Therapy with Slow-Release Compounded Thyroid Replacement
Author(s): Milner Martin
May/Jun 2008
Pg. 200-207
Dilution and Compounding of Ziconotide for Intrathecal Administration
Author(s): Buchta Tony, Fakata Keri, Stuart William
May/Jun 2007
Pg. 247
Levothyroxine Sodium 40-micro-g/mL Oral Liquid
Author(s): Allen Loyd V Jr
Jan/Feb 2023
Pg. 22-23
The U.S. Food and Drug Administration Takes Aim at Compounded Thyroid Hormone
Author(s): Brunner Scott
Jul/Aug 2003
Pg. 297
Chlorpromazine HCl 30-mg/mL Oral Concentrate
Author(s): Allen Loyd V Jr
Jul/Aug 2019
Pg. 320-323
Long-term Physicochemical Stability of Concentrated Solutions of Sodium Valproate in Polypropylene Syringes for Administration in the Intensive Care Unit
Author(s): Lardinois Benjamin, Baltzis Alexandre, Braibant Maximilien, Soumoy Laura, Jamart Jacques, Bihin Benoît, Hecq Jean-Daniel, Galanti Laurence
Nov/Dec 2013
Pg. 505
Levothyroxine Sodium 100-mcg Capsules
Author(s): Allen Loyd V Jr
Sep/Oct 2015
Pg. 414-419
Solid State Stability of Extemporaneously Prepared Levothyroxine Aliquots and Capsules
Author(s): Fortner Jeff, Salton Jason, Carlson Christie, Wheeler Rich, Cote Brianna, Rao Deepa
Jan/Feb 2004
Pg. 46-48
Basics of Compounding for Disorders of the External Ear
Author(s): Allen Loyd V Jr
May/Jun 2004
Pg. 206-209
Basics of Compounding for Cold Sores or Fever Blisters
Author(s): Allen Loyd V Jr
Jan/Feb 2005
Pg. 61
Standard Operating Procedure: Compounding with Concentrated Acids
Author(s): Allen Loyd V Jr