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Basics of Compounding: Basics of Compounding with Aliquots, Dilutions, and Concentrates

Author(s):  Allen Loyd V Jr

Issue:  Nov/Dec 2010 - Volume 14, Number 6
View All Articles in Issue

Abstract:  Pharmacists involved in compounding must consider a number of factors when determining the actual quantity of an active ingredient to use for a compounded prescription. Many drug substances and excipients are available as aliquots, dilutions, and concentrates and do not consist of 100% drug or chemical. Since the bulk substance, or active pharmaceutical ingredient or excipient is not 100% active drug in all cases, then it is important to know the strength of the item so that appropriate allowances can be made to obtain the correct amount.

Related Keywords: acids and bases, calculations, Loyd V. Allen Jr., PhD, RPh, potency, concentration, triturations, nitroglycerin, solutions

Related Categories: EXCIPIENTS, SUPPORT, QUALITY CONTROL

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