Bot Detector
IJPC Seal
Download FREE Sample Issue or Article
LEARN MORE
Subscribe Today
A subscription to IJPC provides on-line access to full-text, full-color, printable PDF copies of your subscribed issues, individual articles, and purchased archives.

Orodispersible Films for Compounding Pharmacies

Author(s):  Ferreira Anderson O, Brandão Marcos Antônio F, Raposo Francisco José, Polonini Hudson C, Raposo Nádia Rezende Barbosa

Issue:  Nov/Dec 2017 - Volume 21, Number 6
View All Articles in Issue

Page(s):  454-461

Orodispersible Films for Compounding Pharmacies Page 1
Orodispersible Films for Compounding Pharmacies Page 2
Orodispersible Films for Compounding Pharmacies Page 3
Orodispersible Films for Compounding Pharmacies Page 4
Orodispersible Films for Compounding Pharmacies Page 5
Orodispersible Films for Compounding Pharmacies Page 6
Orodispersible Films for Compounding Pharmacies Page 7
Orodispersible Films for Compounding Pharmacies Page 8

Download in electronic PDF format for $75

Abstract:  Orodispersible film can be defined as a solid pharmaceutical form intended for the delivery and rapid local or systemic release of active ingredients, consisting of a water-soluble polymer film that hydrates rapidly, adhering and dissolving immediately when placed on the tongue or in the oral cavity (oral, palatal, gingival, lingual, or sublingual), without the need for water administration or mastication. Due to its outstanding importance in cases of emergency, practicality of use by patients in transit, and high adherence, orodispersible film has evolved in popularity and success among consumers. It is a promising dosage form for compounding pharmacies, as simpler technologies are being developed to make the compound process easier and faster for the pharmacist. This article aims to explore some of the basics on orodispersible film and the main possible preparations to be developed in compounding pharmacies worldwide.

Related Keywords: Anderson O. Ferreira, BPharm, PhD Candidate, Marcos Antônio F. Brandão, BPharm, PhD, Francisco José Raposo, B Eng, MSC, Hudson C. Polonini, BPharm, PhD, orodispersible film, water-soluble polymer film, dissolve, rapid dissolution, oral administration, oral soluble film, plasticizers, surfactants, saliva-stimulating agents, active pharmaceutical ingredients, solvent casting method, semisolid casting method, hot melt extrusion method, rolling method, quality control testing, Nádia Rezende Barbosa Raposo, BPharm, PhD, patient acceptance, bioavailability

Related Categories: EXCIPIENTS, TECHNOLOGY, QUALITY CONTROL, DOSAGE FORMS/DRUG CARRIERS

Printer-Friendly Version



Related Articles from IJPC
Title/Author
(Click for Abstract / Details / Purchase)
Issue/​Page
View/Buy
Orodispersible Films for Compounding Pharmacies
Ferreira Anderson O
, Brandão Marcos Antônio F, Raposo Francisco José, Polonini Hudson C, Raposo Nádia Rezende Barbosa
Nov/Dec 2017
Pg. 454-461

Compounded Orodispersible Films with Natural Ingredients for Halitosis: A Clinical Experience
Apolinário Régis De Souza
, Chaves Maria Das Graças Afonso Miranda, Gonçalves Hanny Reis Mockdeci, Martins Isadora Conde Ferreria, De Paula Renée Mazilão, Granato Ana Paula Alves, Polonini Hudson Caetano, Brandão Marcos Antônio Fernandes, Ferreira Anderson De Oliveira, Raposo Nádia Rezende Barbosa
Nov/Dec 2018
Pg. 512-515

Investigation of Filler Effects on the Compounding of Freeze-dried Orodispersible Tablets Containing Annona muricata Extract
Azman Syahiera Ezzah Noor
, Abd Razak Fashli Syafiq, Kamal Wan Hamirul Bahrin Wan, Zheng Gan Kok, Ming Long Chiau, Uddin ABM Helal, Sarker Zaidul Islam, Bin Liew Kai
Nov/Dec 2020
Pg. 509-514

Compounding and Characterization of Oral Disintegrating Films Containing Memantine Hydrochloride for Geriatrics
Rofiq Hanifah Mohd
, Phang Hiu Ching, Janakiraman Ashok Kumar, Chew Yik-Ling, Uddin ABM Helal, Sarker Zaidul Islam, Lee Siew-Keah, Liew Kai Bin
Nov/Dec 2023
Pg. 512-521

The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded Levothyroxine Suspensions
Svirskis Darren
, Lin Shao-Wei, Brown Helen, Sangaroomthong Annie, Shin Daniel, Wang Ziqi, Xu Hongtao, Dean Rebecca, Vareed Preetika, Jensen Maree, Wu Zimei
Mar/Apr 2018
Pg. 164-171

Stability of Alprazolam, Atropine Sulfate, Glutamine, Levofloxacin, Metoprolol Tartrate, Nitrofurantoin, Ondansetron Hydrochloride, Oxandrolone, Pregabaline, and Riboflavin in SyrSpend SF pH4 Oral Suspensions
de Oliveira Ferreira Anderson
, Polonini Hudson C, Loures da Silva Sharlene, Cerqueira de Melo Victor Augusto, de Andrade Laura, Fernandes Brandão Marcos Antônio
May/Jun 2017
Pg. 255-263

Comparison of Disintegrant-addition Methods on the Compounding of Orodispersible Tablets
Mahesparan Vishnu A/L
, Bin Abd Razak Fashli Syafiq, Ming Long Chiau, Uddin ABM Helal, Sarker Md Zaidul Islam, Bin Liew Kai
Mar/Apr 2020
Pg. 148-155

Stability of Acetazolamide, Baclofen, Dipyridamole, Mebeverine Hydrochloride, Propylthiouracil, Quinidine Sulfate, and Topiramate Oral Suspensions in SyrSpend SF PH4
de Oliveira Ferreira Anderson
, Polonini Hudson, Loures da Silva Sharlene, Buzinari Aglio Natália Cristina, Abreu Jordana, Fernandes Brandão Marcos Antônio
Jul/Aug 2017
Pg. 339-346

Chemical Stability of Extemporaneously Compounded Omeprazole Formulations: A Comparison of Two Methods of Compounding
Garg Sanjay
, Svirskis Darren, Al-Kabban Majid, Farhan Samer, Komeshi Mohammed, Lee Jacky, Liu Quincy, Naidoo Sacha, Kairuz Therese
May/Jun 2009
Pg. 250-253

Compatibility of Baclofen, Carvedilol, Hydrochlorothiazide, Mercaptopurine, Methadone Hydrochloride, Oseltamivir Phosphate, Phenobarbital, Propranolol Hydrochloride, Pyrazinamide, Sotalol Hydrochloride, Spironolactone, Tacrolimus Monohydrate, Ursodeoxycholic Acid, and Vancomycin Hydrochloride Oral Suspensions Compounded with SyrSpend SF pH4
Polonini Hudson
, da Silva Sharlene Loures, Brandão Marcos Antônio Fernandes, Bauters Tiene, De Moerloose Barbara, Ferreira Anderson de Oliveira
Nov/Dec 2018
Pg. 516-526

Formulation and Pharmaceutical Evaluation of Extemporaneous α-arbutin Creams for the Treatment of Melasma
Teeranachaideekul Veerawat
, Boonsongsawat Worrawee, Asanawittaya Waralee, Jintapattanakit Anchalee, Chantasart Doungdaw, Wongrakpanich Amaraporn
Jan/Feb 2021
Pg. 62-72

An Exploratory Study of Suboxone (Buprenorphine/Naloxone) Film Splitting: Cutting Methods, Content Uniformity, and Stability
Reindel Kristin L
, DeAngelis Michael J, Ferrara Alexander S, Conn Kelly M, Phillips Elizabeth M, Corigliano Anthony T, Zhao Fang
May/Jun 2019
Pg. 258-263

Towards the Importance of a Roller Mill in Compounding Practice: An Experimental Approach
Polonini Hudson
, Loures da Silva Sharlene, Batista Patrício Fernando, Fernandes Brandão Marcos Antônio, de Oliveira Ferreira Anderson
Mar/Apr 2019
Pg. 154-156

Basics of Compounding: Compounding Films
Allen Loyd V Jr
Jul/Aug 2016
Pg. 298-305

Stability of Allopurinol, Amitriptyline Hydrochloride, Carbamazepine, Domperidone, Isoniazid, Ketoconazole, Lisinopril, Naproxen, Paracetamol (Acetaminophen), and Sertraline Hydrochloride in SyrSpend SF PH4 Oral Suspensions
Polonini Hudson C
, Loures Sharlene, de Araujo Edson Peter, Brandão Marcos Antônio F, Ferreira Anderson O
Sep/Oct 2016
Pg. 426-434

Stability of Atenolol, Clonazepam, Dexamethasone, Diclofenac Sodium, Diltiazem, Enalapril Maleate, Ketoprofen, Lamotrigine, Penicillamine-D, and Thiamine in SyrSpend SF PH4 Oral Suspensions
Polonini HC
, Loures S, Lima LC, Ferreira AO, Brandão MA
Mar/Apr 2016
Pg. 167-174

Setting Up a National System of Compounding Pharmacies: Preventing Error, Assuring Quality, Building Trust
Guedes de Souza Hugo
, Favaro Alvaro Jr, Andrade Alba Livia, Gomes Lenir Yago, de Souza Aguiar Simone, do Carmo Garcez Maria
Nov/Dec 2009
Pg. 532-536

Development of a Novel Co-processed Excipitient Comprising of Xylitol, Mannitol, Microcrystalline Cellulose, and Crospovidone for the Compounding of Memantine Hydrochloride Orally Disintegrating Tablet
Hazdi Siti Nursaqifah
, Phang Hiu Ching, Ng Zhi Qi, Chew Yik Ling, Uddin ABM Helal, Sarker Zaidul Islam, Lee Siew-Keah, Liew Kai Bin
Nov/Dec 2023
Pg. 522-527

PostScription: Setting up a National System of Compounding Pharmacies: An Introduction
Guedes de Souza Hugo
, Favaro Alvaro Jr, Andrade Alba Livia, Gomes Lenir Yago, de Souza Aguiar Simone, do Carmo Garcez Maria
Sep/Oct 2009
Pg. 447

Transdermal Delivery of Metformin Hydrochloride from a Semisolid Vehicle
Polonini Hudson
, Lopes Cândido Paulo José, Andrade Junquiera Laura, Loures Sharlene, Raposo Nádia RB, Fernandes Brandão Marcos Antônio, de Oliveira Ferreira Anderson
Jan/Feb 2019
Pg. 65-69

Return to Top