Abstract

Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants

Author(s): Allen Loyd V Jr

Issue: Sep/Oct 2020 - Volume 24, Number 5

Page(s): 388-395

Download in electronic PDF format for $75
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 1
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 2
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 3
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 4
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 5
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 6
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 7
  • Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants Page 8

Abstract

Surfactants have many applications in pharmacy. However, they must be used appropriately to prevent poor formulations and difficulties in measuring doses due to foaming, etc. It is not difficult to determine which surfactant is appropriate for different applications, to determine the appropriate hydrophilic lipophilic balance system to be used, to blend surfactants if needed, and to prepare them correctly to minimize any adverse effect on the final preparation. This article discusses several types of substances that have surfactant properties (anionic surfactants, cationic surfactants, nonionic surfactants, poloxamers) and their applications.

Related Keywords

  • nonsterile compounding
  • surfactants
  • surface-acting agents
  • hydrophilic lipophilic balance
  • anionic surfactants
  • cationic surfactants
  • nonionic surfactants
  • poloxamers
  • solubilization
  • solubility
  • micelle formation
  • stability
  • emulsions
  • emulsification
  • miscibility
  • microemulsions
  • immiscible liquids
  • suspensions
  • parenteral preparations
  • oral films
  • tablets
  • capsules
  • transdermal preparations
  • dermal penetration
  • otic irrigating solutions
  • wetting agents
  • respiratory therapy
  • laxatives
  • nasal preparations
  • detergents
  • ophthalmic preparations
  • foaming

Related Categories

  • EXCIPIENTS
  • OPHTHALMICS
  • PARENTERALS
  • DOSAGE FORMS/DRUG CARRIERS

Printer-Friendly Version

Related Articles from IJPC

Issue/Page
View/Buy		 Title/Author
(Click for Abstract / Details / Purchase)
Sep/Oct 2020
Pg. 388-395
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 7: Compounding with Surfactants
Author(s): Allen Loyd V Jr
May/Jun 2004
Pg. 181-185
Compounding in the Pharmacy Curriculum: Beyond the Basics
Author(s): Hinkle Amanda R, Newton Gail D
Sep/Oct 2020
Pg. 358-364
Cocamidopropyl Betaine Surfactant 0.075% Solution in Physiological Serum for Hygiene Process of COVID-19 Intubated Patients
Author(s): Nogales Luis Marcos, Jiménez Labaig Luis, Abarca Lachén Edgar, Gil Melcón María, López-Nieves Marisol
Jul/Aug 2004
Pg. 269-274
Current Topical Treatments in Wound Healing - Part 1
Author(s): Helmke Christopher D
Jul/Aug 2019
Pg. 305-311
Basics: Excipients Used in Nonsterile Compounding, Part 1
Author(s): Allen Loyd V Jr
Jan/Feb 2020
Pg. 38-43
Basics: Excipients Used in Nonsterile Compounding, Part 4: Antioxidants and Chelating Agents
Author(s): Allen Loyd V Jr
May/Jun 2020
Pg. 206-212
Basics: Excipients Used in Nonsterile Compounding, Part 6: Compounding with Viscosity-increasing Agents
Author(s): Allen Loyd V Jr
Sep/Oct 2021
Pg. 396-400
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 11: Drug Tastes: Innate, Induced, and Improved
Author(s): Allen Loyd V Jr
Mar/Apr 2022
Pg. 118-126
Basics of Compounding: Compounding Nonsterile Preparations Using Cyclodextrins
Author(s): Allen Loyd V Jr
Nov/Dec 2019
Pg. 472-477
Basics: Excipients Used in Nonsterile Compounding, Part 3: Preservatives
Author(s): Allen Loyd V Jr
Sep/Oct 2019
Pg. 393-396
Basics: Excipients Used in Nonsterile Compounding, Part 2
Author(s): Allen Loyd V Jr
Jul/Aug 2017
Pg. 301-308
Basics of Sterile Compounding: Excipients Used in Injections
Author(s): Akers Michael J
Sep/Oct 2023
Pg. 431-439
The Influence of Polymers, Surfactants, and Other Excipients on Naproxen Sodium Release from Matrices Prepared and the Effect of These Additives on the Swelling Rate of the Tablet
Author(s): Alhmoud Hassan, Akkam Yazan, Omari Derar, Alghananim Alaa, Melhem Mohammad Bani
Mar/Apr 2020
Pg. 114-118
Basics of Nonsterile Compounding: Excipients Used in Nonsterile Compounding, Part 5: Compounding Using Solvents and Cosolvent Systems
Author(s): Allen Loyd V Jr
May/Jun 2004
Pg. 206-209
Basics of Compounding for Cold Sores or Fever Blisters
Author(s): Allen Loyd V Jr
Nov/Dec 2021
Pg. 486-489
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 12: Sorbents (Adsorbents and Absorbents)
Author(s): Allen Loyd V Jr
Jul/Aug 2021
Pg. 304-309
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 10: Rectal Suppository Bases
Author(s): Allen Loyd V Jr
Jan/Feb 2012
Pg. 64-68
Basics of Compounding: Implementing United States Pharmacopeia Chapter <795> Pharmaceutical Compounding–Nonsterile Preparations, Part 4
Author(s): Allen Loyd V Jr
Sep/Oct 2018
Pg. 387-398
Compounding Enclosures: Ensuring Safety During the Preparation of Sterile and Nonsterile Formulations
Author(s): Ashe Krystina, Baskett Dustin
Mar/Apr 2021
Pg. 126-128
Basics of Compounding: Excipients Used in Nonsterile Compounding, Part 8: Humectants
Author(s): Allen Loyd V Jr