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Basics: Considerations and Background Information for Counseling Patients Using Compounded Suppositories

Author(s):  Allen Loyd V Jr

Issue:  Jan/Feb 2022 - Volume 26, Number 1
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Abstract:  Suppositories are unique dosage forms and provide pharmacists with an opportunity for a detailed discussion when counseling a patient. In addition to explaining an appropriate method of administration, there are several other factors that should be explained to the patient to enhance compliance, which includes various physiological factors; physicochemical properties; and other characteristics of the active drug and suppository base to enhance convenience, understanding, and compliance. Applicable background information is provided to enable a knowledgeable consultation by the pharmacist.

Related Keywords: Loyd V. Allen Jr., PhD, RPh, patient counseling, suppository, transrectal administration, rectal preparation, rectal absorption, lipid-water miscibility-solubility, drug particle size, excipients, rectal intolerance, drug instability, base instability, adverse effects, bioavailability


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