Abstract
Basics of Sterile Compounding: Intravenous Admixture Preparation Considerations, Part 10: Packaging and Container-closure Issues
Author(s): Allen Loyd V Jr
Issue: Jul/Aug 2021 - Volume 25, Number 4
Page(s): 311-317
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Abstract
The compounding of intravenous admixtures requires knowledge of the packaging and container-closure issues, including their composition, physicochemical characteristics, and tendency towards producing particulates as well as sorption issues. In this article, we will look at containers, closure systems, and sorption issues related to compatibility and stability. Part 11 of this series will discuss particulates in intravenous admixtures.
Related Keywords
- compounded sterile preparations
- drug admixtures
- intravenous administration
- packaged parenterals
- container closure integrity
- containers
- prefilled syringe products
- prefilled cartridge systems
- silicone
- packaging materials
- lyophilized products
- closure materials
- stability
- compatibility
- permeability
- oxidative degradation
- leaching
- sorption
- adsorption
- absorption
Related Categories
- PACKAGING
- STERILE PREPARATIONS
- QUALITY CONTROL
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