Abstract
Sterile Basics: Intravenous Admixture Compounding, Part 1: Introduction and Overview of the General Guidelines for an Intravenous Admixture Compounding Program, and Compounding Personnel Considerations
Author(s): Allen Loyd V Jr
Issue: Mar/Apr 2023 - Volume 27, Number 2
Page(s): 123-139
Abstract
Intravenous admixture compounding is a common practice in most hospitals throughout the world, regardless of the country. Due to the complexity in compounding intravenous medications, there is a high potential for error, and since intravenous medications must be compounded in an aseptic environment, this poses additional issues for the compounder. Part 1 of this series of articles provides an introduction, an overview, and compounding personnel considerations of this topic. The remaining parts of this series will cover parenteral vehicle considerations; preparation procedures; physicochemical considerations; handling potential incompatibilities; endotoxin considerations; and quality control of intravenous admixtures. This introductory article in this overall series on intravenous admixture preparation presents issues related to their compounding and to medication error prevention.
Related Keywords
- intravenous admixtures
- hospital pharmacy
- compounded sterile preparations
- aseptic technique
- compounding personnel
- drug errors
- commercial products
- contamination
- incompatibility
- chemical stability
- United States Pharmacopeia Chapter <797>
- USP
- drug safety
- microbial contaminants
- bacterial endotoxins
- patient-controlled analgesia
- quality control
- small-volume injections
- large-volume parenterals
- infusions
- maintenance therapy
- electrolyte replacement
- total parenteral nutrition
- cleanroom processes
- standardization of intravenous concentrations
Related Categories
- PARENTERALS
- STERILE PREPARATIONS
- QUALITY CONTROL
- UNITED STATES PHARMACOPEIA CONVENTIONS
- HOSPITAL PHARMACY
- INFORMATION RESOURCES
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