Abstract

Basics of Sterile Compounding: Sterile Basics of Compounding Intravenous Admixtures, Part 4: Physicochemical Considerations

Author(s): Allen Loyd V Jr

Issue: Sep/Oct 2023 - Volume 27, Number 5

Page(s): 397-409

Download in electronic PDF format for $75

Abstract

Intravenous admixture compounding is common practice in most hospitals throughout the world, regardless of the country. Compounding intravenous medications involves risk, as there is a high potential for error due to their complexity in compounding as well as the additional issues that working in an aseptic compounding environment poses for the compounder. This article in a series of intravenous admixture compounding discusses considerations involved when using commercial products in compounding, as well as a discussion on the issues of freezing, solubility, sorption, leaching, incompatibilities, and quality control, with an emphasis on physicochemical considerations.

Related Keywords

Related Categories

Printer-Friendly Version

Related Articles from IJPC

Issue/Page View/Buy	Title/Author (Click for Abstract / Details / Purchase)
Sep/Oct 2023 Pg. 397-409	Basics of Sterile Compounding: Sterile Basics of Compounding Intravenous Admixtures, Part 4: Physicochemical Considerations Author(s): Allen Loyd V Jr
Mar/Apr 2021 Pg. 131-139	Intravenous Admixture Preparation Considerations, Part 9-A: Error Prevention in Intravenous Admixture Preparation Author(s): Allen Loyd V Jr
May/Jun 2021 Pg. 222-229	Intravenous Admixture Preparation Considerations, Part 9-B: Error Prevention in Intravenous Admixture Preparation Author(s): Allen Loyd V Jr
Jul/Aug 2023 Pg. 305-313	Sterile Basics of Compounding: Intravenous Admixture Compounding, Part 3: Preparation Procedures Author(s): Allen Loyd V Jr
May/Jun 2023 Pg. 223-229	Sterile Basics: Intravenous Admixture Compounding, Part 2: Parenteral Vehicle Considerations Author(s): Allen Loyd V Jr
Mar/Apr 2023 Pg. 123-139	Sterile Basics: Intravenous Admixture Compounding, Part 1: Introduction and Overview of the General Guidelines for an Intravenous Admixture Compounding Program, and Compounding Personnel Considerations Author(s): Allen Loyd V Jr
May/Jun 2020 Pg. 215-220	Sterile Basics: Intravenous Admixture Preparation Considerations, Part 4: Particulates Author(s): Allen Loyd V Jr
Jul/Aug 2020 Pg. 305-309	Sterile Basics: Intravenous Admixture Preparation Considerations, Part 5: pH Considerations Author(s): Allen Loyd V Jr
Jul/Aug 2021 Pg. 311-317	Basics of Sterile Compounding: Intravenous Admixture Preparation Considerations, Part 10: Packaging and Container-closure Issues Author(s): Allen Loyd V Jr
May/Jun 2004 Pg. 181-185	Compounding in the Pharmacy Curriculum: Beyond the Basics Author(s): Hinkle Amanda R, Newton Gail D
Nov/Dec 2019 Pg. 478-482	Intravenous Admixture Preparation Considerations, Part 1: Overview of Series on Personnel Selection for Intravenous Admixture Compounding Author(s): Allen Loyd V Jr
Jan/Feb 2021 Pg. 31-38	Intravenous Admixture Preparation Considerations, Part 8: Ready-to-Use Preparations Author(s): Allen Loyd V Jr
Jan/Feb 2020 Pg. 44-50	Intravenous Admixture Preparation Considerations, Part 2: Incompatibilities and Factors Involved Author(s): Allen Loyd V Jr
Nov/Dec 2021 Pg. 491-496	Basics of Sterile Compounding: Intravenous Admixture Preparation, Part 12: United States Pharmacopeia Chapters Referenced in the Current United States Pharmacopeia Chapter <797> Pharmaceutical Compounding -- Sterile Preparations Author(s): Allen Loyd V Jr
May/Jun 2022 Pg. 219-228	Sterile Basics of Compounding: Particulates in Parenteral Preparations: Sources, Minimization, and Detection Author(s): Allen Loyd V Jr
Jan/Feb 2022 Pg. 41-49	Sterile Basics: Compounding Sterile Preparations with Cyclodextrins Author(s): Allen Loyd V Jr
Sep/Oct 2020 Pg. 397-402	Intravenous Admixture Preparation Considerations, Part 6: pH Considerations -- Applications Author(s): Allen Loyd V Jr
Sep/Oct 2018 Pg. 387-398	Compounding Enclosures: Ensuring Safety During the Preparation of Sterile and Nonsterile Formulations Author(s): Ashe Krystina, Baskett Dustin
Nov/Dec 2020 Pg. 473-478	Intravenous Admixture Preparation Considerations, Part 7: Stability Issues Author(s): Allen Loyd V Jr
Sep/Oct 2022 Pg. 411-418	Sterile Basics of Compounding: Contamination Control Strategies, Part 1 Author(s): Summers Amy