Sterile Basics: Intravenous Admixture Compounding, Part 2: Parenteral Vehicle Considerations
Author(s): Allen Loyd V Jr
Issue: May/Jun 2023 - Volume 27, Number 3
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Page(s): 223-229
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Abstract: Intravenous admixture compounding is a common practice in most hospitals throughout the world, regardless of the country. The compounding of intravenous medications, however, involves risk, as there is a high potential for error due to their complexity in compounding. Also, working in an aseptic environment itself poses issues for the compounder. This article in an overall series on the topic of intravenous admixture compounding will discuss the vehicles commonly used in intravenous admixtures, as well as the small-volume parenterals often used in compounding intravenous admixtures.
Related Keywords: Loyd V. Allen Jr., PhD, RPh, intravenous admixtures, aseptic environment, parenteral administration, compounding vehicles, small-volume parenteral product, compounded sterile preparations, aqueous vehicles, nonaqueous, water miscible vehicles, nonaqueous, water immiscible vehicles, solubility, stability, pH, compatibility, tonicity, sterilization method
Related Categories: EXCIPIENTS, PARENTERALS, STABILITIES, COMPATIBILITIES, STERILE PREPARATIONS