Compatibility and Stability of Potassium Chloride and Magnesium Sulfate in 0.9% Sodium Chloride Injection and 5% Dextrose Injection Solutions

Quay, Irene; Tan, Edward

Abstract

Compatibility and Stability of Potassium Chloride and Magnesium Sulfate in 0.9% Sodium Chloride Injection and 5% Dextrose Injection Solutions

Author(s): Quay Irene, Tan Edward

Issue: Jul/Aug 2001 - Sterile Product Compounding

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Page(s): 323-324

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Abstract

The compatibility and stability of 80 mmol/L potassium chloride and 16 mmol/L magnesium sulfate in 0.9% sodium chloride injection and in 5% dextrose injection solutions at 22°C have been studied by means of a Beckman Clinical Chemistry Analyzer Synchron CX5 Delta. The infusions were stable for 24 hours at 22°C. The results from both diluents showed an average of ± 5% fluctuations in concentration. None of the samples appeared to form visible precipitation or to change in color or clarity.

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