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Case Report of Anal Fissures and Hemorrhoids Treated with Compounded Cromolyn Sodium and Naltrexone Hydrochloride in MEDISCA's SPG SUPPOSI-BASE

Author(s):  Earlywine Kerry, Haiub Halema, Cull Erica, Lupatini Rodrigo, Sidhu Raman

Issue:  Jan/Feb 2023 - Volume 27, Number 1
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Page(s):  6-10

Case Report of Anal Fissures and Hemorrhoids Treated with Compounded Cromolyn Sodium and Naltrexone Hydrochloride in MEDISCA's SPG SUPPOSI-BASE Page 1
Case Report of Anal Fissures and Hemorrhoids Treated with Compounded Cromolyn Sodium and Naltrexone Hydrochloride in MEDISCA's SPG SUPPOSI-BASE Page 2
Case Report of Anal Fissures and Hemorrhoids Treated with Compounded Cromolyn Sodium and Naltrexone Hydrochloride in MEDISCA's SPG SUPPOSI-BASE Page 3
Case Report of Anal Fissures and Hemorrhoids Treated with Compounded Cromolyn Sodium and Naltrexone Hydrochloride in MEDISCA's SPG SUPPOSI-BASE Page 4
Case Report of Anal Fissures and Hemorrhoids Treated with Compounded Cromolyn Sodium and Naltrexone Hydrochloride in MEDISCA's SPG SUPPOSI-BASE Page 5

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Abstract:  The purpose of this case report is to evaluate and demonstrate the benefits of compounded therapy in treating chronic rectal fissures with hemorrhoids using a compounded suppository containing cromolyn sodium and naltrexone hydrochloride in MEDISCA’s SPG SUPPOSI-BASE. The primary outcomes of symptomatic improvement and healed fissure were reported and confirmed by the practitioner and, via self-assessment, by the patient, which was observed after a long-troubled history of failed treatments. The case had no side effects or complications, and the patient reported a full recovery after using this compounded therapy for ten days.

Related Keywords: Kerry Earlywine, PharmD, Halema Haiub, MSc, Erica Cull, BSc, Rodrigo Lupatini, MSc, Raman Sidhu, BSc, case report, anal fissures, chronic rectal fissures, anorectal administration, cromolyn sodium, naltrexone hydrochloride, hemorrhoids, topical preparations, anal sphincter relaxants, piles, anal bleeding, rectal suppository, formulation, SPG SUPPOSI-BASE, inflammation

Related Categories: EXCIPIENTS, FORMULATIONS, GASTROENTEROLOGY, WOUND CARE, CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS

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